Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Several types of travel increase risk of venous thrombosis

22.08.2006
Traveling for more than 4 hours by air, car, bus or train is associated with an increased risk of venous thrombosis.

In a large study (the MEGA study) of nearly 2000 people with a first thrombosis in the Netherlands, Dr Suzanne Cannegieter and colleagues from the Leiden University Medical Center looked at the risk factors for thrombosis compared with their partners, who did not have thrombosis. The results, published in the international open-access medical journal PLoS Medicine, showed that 233 of the people with thrombosis had traveled for more than 4 h in the 8 weeks preceding the event. Although the overall risk of developing thrombosis is still low, traveling in general was found to increase the risk of venous thrombosis 2-fold. The risk was highest in the first week after traveling, and the overall risk of flying was largely similar to the risks of traveling by car, bus, or train.

In particular groups of people the risk was increased. For example, the risk was up to 8-fold in people who also had a specific mutation in one of the genes involved in clotting (factor V Leiden); almost 10-fold in those who had a body mass index of more than 30 kg/m2; 4-fold in those who were more than 1.90 m tall; and more than 20-fold in those who used oral contraceptives. For air travel these findings of risk in particular groups were more apparent than for other modes of travel, and in addition, people shorter than 1.60 m had an almost 5-fold risk of thrombosis after air travel. However, the numbers of people in each of these groups was small and hence the estimates of risk must be interpreted carefully.

The authors conclude that the risk of venous thrombosis is moderately increased for all these modes of travel, and that in particular groups of people the risk is highly increased. The study could not show the mechanism of the increased risk, although the association of thrombosis with all types of travel, not just air travel, suggests that immobility is a key factor. Other mechanisms, such as reduced oxygen levels triggering clotting, may be involved in the particularly increased risk seen in air travel in some groups.

For those who have an increased risk, such as oral contraceptive users and individuals with factor V Leiden, the authors say that preventative measure such as exercises may be warranted. However, the study’s results apply only to people younger than 70 y of age and it is likely that other characteristics exist that also increase the risk. These characteristics are being investigated in an ongoing study – the World Health Organization Research Initiative into the Global Hazards of Travel (WRIGHT).

Andrew Hyde | alfa
Further information:
http://www.plos.org
http://www.plosmedicine.org/

More articles from Health and Medicine:

nachricht Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>