While diseases like asthma and allergies are becoming increasingly common in the West, many people believe that we are living ever stressful lives. A new study from Karolinska Institutet (KI) in Sweden backs up what many people have suspected: that there are important links between mental stress and the complex physical inflammation reactions characteristic of allergies.
In order to understand the link between stress and allergy, the scientists have examined how a major medical exam at KI affects feelings of stress, stress hormone levels, the immune system and lung function amongst students with and without allergies. The extensive tests were made on two occasions, first with the students during a calm period of study with no exam in sight, and then shortly before a major exam. Twenty two students with hayfever and/or asthma and 19 healthy students took part.
For the first time on record, scientists were able to show that a group of cells that are central to the human immune system known as regulatory T cells appear to increase sharply in number in response to mental stress. A regulatory T cell is a kind of white blood cell that controls the activity of a number of other types of immune cell. This increase was observed in both groups of students.
The study also showed that blood concentrations of a group of inflammation products called cytokines had changed and shifted against a pattern associated with allergic inflammation in the allergic students, but remained normal in the healthy students.
According to Mats Lekander and Caroline Olgart Höglund, who are leading the research group, the two discoveries might very well be linked.
”There is much to suggest that the regulatory T cells are dysfunctional in people with allergies,” Mats Lekander says. When people become stressed, they increase in number and normally have an anti-inflammatory effect. If this system does not work in people with allergies, it could explain the changed cytokine balance that we have observed in them.”
Katarina Sternudd | alfa
Finnish research group discovers a new immune system regulator
23.02.2018 | University of Turku
Minimising risks of transplants
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy