Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Egg harvesting for stem cell research

14.08.2006
Women’s health and human rights advocates worldwide are increasingly concerned that overzealous pursuit of new scientific discoveries may once again be threatening women’s health. This time, young women are being asked to donate or sell their ova, not only for use in fertility clinics, but increasingly for non-clinical use in experimental cloning research.

Diane Beeson and Abby Lippman, based at California State University and McGill University, Montreal respectively, report on medical risks and ethical problems associated with collection of human oocytes (eggs) during IVF practice from donors who give them to other women who desperately want a child. Doubts are emerging about donating oocytes in this manner, even when recipients use them to establish a pregnancy. Their article Egg harvesting for stem cell research: medical risks and ethical problems is published in the journal Reproductive BioMedicine Online [www.rbmonline.com/Article/2503 – e-pub ahead of print 14 August 2006].

Widely practised in IVF, but not yet proven to be fully safe, various hormones are given to donors to stimulate several eggs to develop. Using ultrasound, ripe oocytes are then aspirated from within their follicles. The oocytes are often donated free, although the HFEA has given permission for donors to receive some compensation via discounts for their own IVF treatment. In one case reported, the donor oocytes were needed for stem cell research, which makes ethicists even more furious about ‘selling’ human oocytes.

It is hard to separate ethically this decision from giving direct payments to donors, or from fertilizing the eggs and then giving them away for research. In all these examples, many donors might have suffered from mild symptoms of ovarian hyperstimulation, among other disorders, without their knowledge.

Recent research has stressed the risks of using hormonal stimulants to induce follicle growth and ovulation in women. Surprisingly, Beeson and Lippman claim that pharmaceutical companies have not been compelled to submit their information on the risks of such forms of ovulation induction to the US Food and Drug Administration. Claims are made of 25 deaths among donors, although this requires verification. Claims that cancers may be induced in some patients have been questioned or denied, although an increase arose in another study on >3500 women donors, and critics stress that many of these studies had short-term follow-ups in only a few women. These patients were among the first to attempt IVF, and their risks of tumours are now emerging and will be analysed in the near future.

IVF children have not yet displayed such anomalies, though significant abnormalities are reported in offspring of mice following similar treatments. These investigating authors nevertheless cited earlier reports on anomalies, including cancers, in offspring of women receiving exogenous hormones, perhaps due to the release of steroids. In view of all these known and unknown risks to women donors, these authors refer to organizations established to protect women undergoing IVF and other ovarian treatments. It is one thing, however, to raise a fuss about uncertain risks but quite another to gain hard data from the complex reports emerging in the world of assisted human conception.

Fiona Bennett | alfa
Further information:
http://www.rbmonline.com/Article/2503

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>