Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


EMBL scientists found start-up company to develop anti-cancer drugs

Elara Pharmaceuticals GmbH provides a fast track from bench to clinical application

Today EMBL scientists, EMBL’s commercial affiliate, EMBL Enterprise Management Technology Transfer GmbH (EMBLEM) and EMBL’s venture vehicle, EMBL Ventures GmbH, announce the foundation of Elara Pharmaceuticals GmbH, a start-up company that will translate basic research findings into new anti-cancer drugs. Elara is a spin-out company dedicated to drug development and will follow-up on promising small molecule leads that have shown powerful anti-cancer actions in screening experiments. Elara receives seed funding from EMBL Ventures and has been granted exclusive license rights to selected discoveries made at EMBL.

“Elara draws on the skills and know-how of some of Europe’s leading molecular biologists and the cutting-edge technology of EMBL’s Chemical Biology Core Facility”, says George Reid, researcher at EMBL and CEO of Elara. “The EMBL core facility, led by Joe Lewis, who is also a co-founder of ELARA, has tested thousands of small molecules in screens developed during our basic research activities, and identified several series with anti-cancer action. Elara will now take the most promising of these compounds, further develop them and then evaluate their activity in animal models of various types of tumours, such as lung and breast cancer. Through creating a direct flow of information from basic research, preclinical development and application studies, we will greatly speed up the process of drug development.”

Elara will follow-up on promising leads of molecules that block the signaling protein Aurora Kinase A, which is strongly over-expressed in cancer cells, and on inhibitors that affect estrogen receptor signaling, a process essential in the development of breast cancer. EMBO Executive Director, EMBL Senior Scientist and Elara co-founder Frank Gannon heads the world-leading research group studying these receptors. Five lead series of bio-active molecules with different modes of action and diverse chemical structures have already been identified from the two cancer-related signaling pathways.

“Traditionally, there is a significant gap between basic research and drug development”, says Christof Antz, Managing Director of EMBL Ventures. “It often takes years to get from promising findings to a therapeutic approach. With Elara we aim to bridge this gap and create a direct pipeline from the Laboratory by way of animal testing to clinical development.”

Anna-Lynn Wegener | alfa
Further information:

More articles from Health and Medicine:

nachricht Inflammation Triggers Unsustainable Immune Response to Chronic Viral Infection
24.10.2016 | Universität Basel

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

First-time reconstruction of infectious bat influenza viruses

25.10.2016 | Life Sciences

Novel method to benchmark and improve the performance of protein measumeasurement techniques

25.10.2016 | Life Sciences

Amazon rain helps make more rain

25.10.2016 | Life Sciences

More VideoLinks >>>