Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

EMBL scientists found start-up company to develop anti-cancer drugs

09.08.2006
Elara Pharmaceuticals GmbH provides a fast track from bench to clinical application

Today EMBL scientists, EMBL’s commercial affiliate, EMBL Enterprise Management Technology Transfer GmbH (EMBLEM) and EMBL’s venture vehicle, EMBL Ventures GmbH, announce the foundation of Elara Pharmaceuticals GmbH, a start-up company that will translate basic research findings into new anti-cancer drugs. Elara is a spin-out company dedicated to drug development and will follow-up on promising small molecule leads that have shown powerful anti-cancer actions in screening experiments. Elara receives seed funding from EMBL Ventures and has been granted exclusive license rights to selected discoveries made at EMBL.

“Elara draws on the skills and know-how of some of Europe’s leading molecular biologists and the cutting-edge technology of EMBL’s Chemical Biology Core Facility”, says George Reid, researcher at EMBL and CEO of Elara. “The EMBL core facility, led by Joe Lewis, who is also a co-founder of ELARA, has tested thousands of small molecules in screens developed during our basic research activities, and identified several series with anti-cancer action. Elara will now take the most promising of these compounds, further develop them and then evaluate their activity in animal models of various types of tumours, such as lung and breast cancer. Through creating a direct flow of information from basic research, preclinical development and application studies, we will greatly speed up the process of drug development.”

Elara will follow-up on promising leads of molecules that block the signaling protein Aurora Kinase A, which is strongly over-expressed in cancer cells, and on inhibitors that affect estrogen receptor signaling, a process essential in the development of breast cancer. EMBO Executive Director, EMBL Senior Scientist and Elara co-founder Frank Gannon heads the world-leading research group studying these receptors. Five lead series of bio-active molecules with different modes of action and diverse chemical structures have already been identified from the two cancer-related signaling pathways.

“Traditionally, there is a significant gap between basic research and drug development”, says Christof Antz, Managing Director of EMBL Ventures. “It often takes years to get from promising findings to a therapeutic approach. With Elara we aim to bridge this gap and create a direct pipeline from the Laboratory by way of animal testing to clinical development.”

Anna-Lynn Wegener | alfa
Further information:
http://www.embl.de
http://www.embl.org/aboutus/news/press/2006/09aug06/index.html

More articles from Health and Medicine:

nachricht Serious children’s infections also spreading in Switzerland
26.07.2017 | Universitätsspital Bern

nachricht New vaccine production could improve flu shot accuracy
25.07.2017 | Duke University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

 
Latest News

CCNY physicists master unexplored electron property

26.07.2017 | Physics and Astronomy

Molecular microscopy illuminates molecular motor motion

26.07.2017 | Life Sciences

Large-Mouthed Fish Was Top Predator After Mass Extinction

26.07.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>