In a study published today in the open access journal BMC Health Services Research, researchers use a mathematical model to show that offering a full cycle of in-vitro fertilisation (IVF) is better value for money for couples and tax-payers than offering multiple cycles of intra-uterine insemination (IUI), followed by IVF if IUI fails. IUI is the treatment currently recommended by the UK National Institute for Clinical Excellence (NICE) for unexplained infertility and male factor subfertility. Although it is cheaper than IVF, IUI requires many more attempts and often fails to result in pregnancy, forcing couples to undergo an IVF cycle after many attempts at IUI.
Nora Pashayan from the Institute of Public Health in Cambridge, UK, collaborated with colleagues to build a mathematical model that evaluates the cost-effectiveness of IVF and that of IUI, followed by IVF if IUI fails. They evaluated the cost of treatment for 100 simulated couples with unexplained infertility and mild male factor subfertility.
Pashayan et al.’s results show that, as IVF is more efficient and more likely to result in pregnancy after the first trial, offering IVF first is more cost-effective than offering IUI alone, or than offering IUI followed by IVF if IUI fails. The amount of money saved if IVF were offered first instead of unstimulated IUI, the least expensive of IUI treatments, would amount to £174,200. This amount of money could pay for IVF treatments for an additional 54 couples.
Juliette Savin | alfa
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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