Might we be able to turn our immune system against another kind of foe besides infections and viruses? How about fat? Researchers from the Centre National de la Recherche Scientifique (CNRS) at the Pasteur Institute and the University of Lille, France, have evidence suggesting the possibility.
The cytokine interleukin-7 (IL-7), an element of the immune system that is critical for maintaining the proper store of immune cells, also prevents obesity-prone mice from getting fat, the researchers report at the 6th International Congress of Neuroendocrinology (ICN 2006) in Pittsburgh June 19 – 22 at the David L. Lawrence Convention Center.
The researchers used a common mouse model for obesity that involves inducing lesions in the hypothalamus--a part of the brain that regulates appetite--using a common food additive, monosodium glutamate (MSG). As expected, these mice packed on extra ounces--up to 28 percent of their normal body weight. Another set of mice was injected with a single infusion of IL-7 after being given MSG. Interestingly, these mice neither developed lesions nor did they gain weight. According to doctoral student Laurence Macia and co-authors, the results indicate for the first time that IL-7 interacts with the hypothalamus, and moreover, this interaction is related to the brain's regulation of appetite. Perhaps the immune and neuroendocrine systems are more closely linked than previously thought, they conclude.
Held in a different part of the world every four years under the auspices of the International Neuroendocrine Federation, this year's congress – Bridging Neuroscience and Endocrinology – is being sponsored by the American Neuroendocrine Society and the University of Pittsburgh School of Medicine. The first full day of the program, June 20, is being held in conjunction with the 10th Annual Meeting of the Society for Behavioral Neuroendocrinology.
Lisa Rossi | EurekAlert!
Finnish research group discovers a new immune system regulator
23.02.2018 | University of Turku
Minimising risks of transplants
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy