This PhD work, carried out by Lluís Samaranch, supports the theory that the majority of patients with MCI are at an intermediate stage which will end up in an acute condition. However, not all cases with mild impairment evolve to this condition.
This conclusion was arrived at after the Memory Disorder Unit at the University Hospital searched for early indicators of the ailment. Besides neuropsychological markers involved, the most significant find was the discovery of PET (Positron Emission Tomography) as a highly efficacious technique for measuring the risk of evolving MCI.
Early detection to combat the disease
This multidisciplinary research involved neuropsychologists, nurses and engineers working together.
For more than 17 months a sample of 299 patients was studied. Of these, 103 suffered some mild cognitive impairment; 80 volunteered subjective complaints regarding memory; and 54 individuals were used as a control group, made up of volunteers from the Navarre Blood Donors’ Association.
All were tested neuropsychologically and with magnetic resonance and were subjected to various analyses and a genetic risk markers examination, amongst other procedures. Thanks to all this, the team came to the conclusion that the illness can be identified at early stages, before irreversible damage occurs, albeit with costly techniques such as the PET.
This is why the team insists on the necessity to find new, more accessible and simpler biochemical markers but with the same predictive capacity. In this manner we can undertake therapeutic intervention in the initial stages of Alzheimer – precisely when there are more possibilities of success.
Irati Kortabitarte | alfa
Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center
Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital
Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
A warming planet
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
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22.09.2017 | Life Sciences
22.09.2017 | Medical Engineering
22.09.2017 | Physics and Astronomy