Researchers funded by the Canadian Institutes of Health Research (CIHR) and the Canadian Diabetes Association (CDA) have identified an unsuspected role of a protein named SHP-1 that could constitute a new therapeutic path against Type 2 Diabetes.
Under the direction of professor André Marette (Laval University), Nicole Beauchemin (McGill University), Martin Oliver (McGill University Health Centre) and Katherine Siminovitch (University of Toronto) were part of a Canadian and American team which published an article in the May issue of Nature Medicine that explains the role of SHP-1 in the control of blood glucose.
The researchers already knew that SHP-1 played a role in regulating the immune system. However, no one had previously taken the time to verify if this protein was involved in the regulation of metabolism. This is precisely what this team of Canadian and American researchers did, thanks to a series of mutant or genetically modified mice producing little or no SHP-1.
Jasmine Sharma | EurekAlert!
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