Nighttime breathing mask decreases blood pressure in people with sleep apnea
Patients with the nighttime breathing disorder known as obstructive sleep apnea who receive air through a mask while they sleep can significantly reduce their blood pressure, according to a study to be presented at the American Thoracic Society International Conference on May 22nd.
"Sleep apnea can have significant consequences on a persons physical health, and this study shows once again that treatment may lessen those risks," said lead researcher Daniel Norman, M.D., Fellow in Pulmonary and Critical Care at the University of California San Diego Medical Center.
In obstructive sleep apnea, the upper airway narrows, or collapses, during sleep. Periods of apnea end with a brief partial arousal that may disrupt sleep hundreds of times a night. More than half of those with sleep apnea also have high blood pressure, and their blood pressure does not fall during sleep as it does in most people.
The most widely used treatment for sleep apnea is a technique called nasal CPAP, for continuous positive airway pressure, which delivers air through a mask while the patient sleeps. It has proved successful in many cases in providing a good nights sleep and preventing daytime accidents due to sleepiness. Supplementary oxygen is sometimes used as a treatment for sleep apnea.
The researchers studied 46 patients with moderate to severe sleep apnea. They were randomly assigned to receive either CPAP treatment, fake CPAP or supplemental nighttime oxygen through a face mask. All patients were hooked up to a 24-hour ambulatory blood pressure monitor, which consists of a small machine strapped to the patients torso that attaches to an arm cuff. The cuff automatically inflates and deflates to measure patients blood pressure.
After two weeks, patients who received the real CPAP treatment had significant reductions in blood pressure during the day and night. Nighttime oxygen therapy did not affect blood pressure.
"There has been some controversy over how sleep apnea causes elevated blood pressure," Dr. Norman said. "Doctors dont know if it is due to drops in oxygen levels or arousals from sleep. Our study indicated that correcting drops in oxygen levels alone may not be enough to reduce blood pressure."
Jim Augustine | EurekAlert!
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
Layered 2D material improves efficiency for solar cells and LEDs
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...