Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Codeine may be no cure for cough

18.05.2006


Scientists at the University of Manchester’s North West Lung Centre have found that codeine - a standard ingredient in cough remedies – could be no more effective than an inactive placebo compound at treating cough.



Researchers at the Centre, which is based at Wythenshawe Hospital, studied a sample of patients with chronic lung disease. After coughing was induced with citric acid they were given either codeine or a placebo, and sent home wearing a lapel microphone to record their coughing during the day and night.

Lead researcher Dr. Jacyln Smith said: “Codeine has long been considered the standard anti-cough agent against which others are measured, but until now little has been known about its impact in patients with chronic lung diseases.


“After the placebo treatment the patients’ coughing fell from an average of 8.27 seconds per hour to 7.22 seconds, and after codeine to 6.41 seconds.

“Although there was a significant reduction after codeine, from a statistical standpoint there was really no difference between codeine and placebo - despite the fact that the dose of codeine used far exceeds that in over-the-counter cough remedies."

The findings were reported in Journal of Allergy and Clinical Immunology, and seem to confirm some medics’ view that reductions in coughing after codeine are attributable to a placebo effect.

Dr Smith concluded: “The effective treatment of chronic dry cough is an important unmet need in patients with chronic respiratory diseases, post-viral coughing and persistent coughing of unknown cause. Studies of cough in other clinical situations are urgently needed if codeine is to be continued to be used as a remedy.”

Jo Nightingale | alfa
Further information:
http://www.manchester.ac.uk/aboutus/news/

More articles from Health and Medicine:

nachricht World first: Massive thrombosis removed during early pregnancy
20.07.2017 | Universitätsspital Bern

nachricht Therapy of preterm birth in sight?
19.07.2017 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA looks to solar eclipse to help understand Earth's energy system

21.07.2017 | Earth Sciences

Stanford researchers develop a new type of soft, growing robot

21.07.2017 | Power and Electrical Engineering

Vortex photons from electrons in circular motion

21.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>