Walking fitness makes a significant difference in predicting the likelihood of future disability in the elderly, according to a study published today in the Journal of the American Medical Association. Researchers at the University of Pittsburgh Graduate School of Public Health (GSPH) and their collaborators found that the ability to walk 400-meters, or about a quarter mile, was an important determinant not only of whether elderly participants would be alive six years later but also how much illness and disability they would experience within that time frame.
"The ability to complete this walk was a powerful predictor of health outcomes. In fact, we found that the people who could not complete the walk were at an extremely high risk of later disability and death," said lead author, Anne B. Newman, M.D., M.P.H., professor of epidemiology at GSPH and professor of medicine in the department of medicine, University of Pittsburgh School of Medicine.
Dr. Newman and her co-workers, collaborating with researchers at five other institutions, asked a group of almost 2,700 community-dwelling white and African-American men and women aged 70 to 79 to complete, as quickly as they could--without running--and at a consistent pace, ten 40-meter laps in a corridor. All of the participants previously had reported no difficulty walking a quarter of a mile, climbing one flight of stairs without resting or performing basic activities of daily living. Participants were excluded from attempting the walk if they had an abnormal electrocardiogram, elevated blood pressure or resting heart rate or recently had a procedure for, or symptoms of, heart disease. Those participants who qualified for the quarter-mile walk were told to stop if they experienced any signs of fatigue or persistent rapid heart rate.
Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center
Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital
Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
A warming planet
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
22.09.2017 | Life Sciences
22.09.2017 | Medical Engineering
22.09.2017 | Physics and Astronomy