Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

The University Of Seville’s Participation In Pulmonary Hypertension Project

02.05.2006


A group of researchers led by Dr. José López Barneo, of the University of Seville and Virgen del Rocío hospital, are taking part in European project PULMOTENSION. The aim of this research project is to fight pulmonary hypertension (PH), a serious illness. PH describes a group of chronic vascular diseases that cause lengthy disability with a fatal ending. It also causes heart failure due to high blood pressure in the lung’s blood vessels, brings shortage of breath, and decreases physical capacity in young and middle-aged patients.



Prof. Antonio Castellano, of the Department of Physiology and Biophysics of the University of Seville, explained to Andalucía Investiga the goal of the research group: ‘We focus on the effects of hypoxia (lack of oxygen) on pulmonary artery smooth muscle cells. When these cells contract, hypertension occurs and blood flow decreases’.

This multidisciplinary collaboration comprises 31 prestigious institutions of the European Union (EU). Two of the groups are from Spain – the one from Seville and another one from the Hospital Clinic i Provincial of Barcelona, coordinated by Dr. Joan Albert Barberá. Associated companies from 12 countries will also work with these organizations.


The EU is funding the PULMOTENSION project with an amount of 11.4 million Euros over a period of four years. Recently, the leaders of this project have held a meeting to set up the consortium. Researchers have elected a management committee and have also set the research strategies, clinical trials and a European registry for a PH tissue bank.

Antonio Castellano pointed out to Andalucía Investiga the techniques used by the team led by Dr. López Barneo- firstly, molecular biology; secondly, ‘electrophysiological techniques, specifically the registration of ionic currents’, at a cellular level- he said. The third group of techniques includes ‘microfluidic techniques, which are used to measure the intracellular calcium concentration’.

The groups associated to PULMOTENSION have made relevant scientific contributions, which range from the initial discovery of mutations causative of PH to the implementation of new therapies for this disease.

Ismael Gaona | alfa
Further information:
http://www.andaluciainvestiga.com

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Thanks for the memory: NIST takes a deep look at memristors

22.01.2018 | Materials Sciences

Radioactivity from oil and gas wastewater persists in Pennsylvania stream sediments

22.01.2018 | Earth Sciences

Saarland University bioinformaticians compute gene sequences inherited from each parent

22.01.2018 | Life Sciences

VideoLinks Wissenschaft & Forschung
Overview of more VideoLinks >>>