Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

The University Of Seville’s Participation In Pulmonary Hypertension Project

02.05.2006


A group of researchers led by Dr. José López Barneo, of the University of Seville and Virgen del Rocío hospital, are taking part in European project PULMOTENSION. The aim of this research project is to fight pulmonary hypertension (PH), a serious illness. PH describes a group of chronic vascular diseases that cause lengthy disability with a fatal ending. It also causes heart failure due to high blood pressure in the lung’s blood vessels, brings shortage of breath, and decreases physical capacity in young and middle-aged patients.



Prof. Antonio Castellano, of the Department of Physiology and Biophysics of the University of Seville, explained to Andalucía Investiga the goal of the research group: ‘We focus on the effects of hypoxia (lack of oxygen) on pulmonary artery smooth muscle cells. When these cells contract, hypertension occurs and blood flow decreases’.

This multidisciplinary collaboration comprises 31 prestigious institutions of the European Union (EU). Two of the groups are from Spain – the one from Seville and another one from the Hospital Clinic i Provincial of Barcelona, coordinated by Dr. Joan Albert Barberá. Associated companies from 12 countries will also work with these organizations.


The EU is funding the PULMOTENSION project with an amount of 11.4 million Euros over a period of four years. Recently, the leaders of this project have held a meeting to set up the consortium. Researchers have elected a management committee and have also set the research strategies, clinical trials and a European registry for a PH tissue bank.

Antonio Castellano pointed out to Andalucía Investiga the techniques used by the team led by Dr. López Barneo- firstly, molecular biology; secondly, ‘electrophysiological techniques, specifically the registration of ionic currents’, at a cellular level- he said. The third group of techniques includes ‘microfluidic techniques, which are used to measure the intracellular calcium concentration’.

The groups associated to PULMOTENSION have made relevant scientific contributions, which range from the initial discovery of mutations causative of PH to the implementation of new therapies for this disease.

Ismael Gaona | alfa
Further information:
http://www.andaluciainvestiga.com

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

New technology for mass-production of complex molded composite components

23.01.2017 | Process Engineering

Quantum optical sensor for the first time tested in space – with a laser system from Berlin

23.01.2017 | Physics and Astronomy

The interactome of infected neural cells reveals new therapeutic targets for Zika

23.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>