Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

NYU, Austrian researchers create non-invasive imaging method with advantages over conventional MRI

25.04.2006


New York University’s Alexej Jerschow, an assistant professor of chemistry, and Norbert Müller, a professor of chemistry at the University of Linz in Austria, have developed a completely non-invasive imaging method. Their work offers the benefits of magnetic resonance imaging (MRI) while eliminating patients’ exposure to irradiation and setting the stage for the creation of light, mobile MRI technology. The research, which appears in the latest issue of the Proceedings of the National Academy of Sciences (PNAS), was supported by the National Science Foundation.

MRI allows clinicians to non-invasively visualize soft tissue in the interior of the human body through the application of radiofrequency (rf) irradiation. However, the rf pulses of MRI machines deposit heat in patients and medical staff, though safety regulations that limit energy deposition have long been established. Jerschow and Müller have devised a low-energy, nuclear magnetic resonance (NMR) technique that does not require external rf-irradiation. Their technique, instead, relies on the detection of spontaneous, proton spin-noise in a tightly coupled rf-cavity.

In order to reconstruct spin-noise images that characterize MRI, the researchers used a commercial, liquid-state NMR spectrometer equipped with a cryogenically cooled probe. The sample, a phantom of four glass capillaries filled with mixtures of water and heavy water, remained at room temperature. The authors inserted the sample into a standard NMR tube and applied a magnetic field gradient to acquire spatial encoding information. They collected 30, one-dimensional images, and after applying a projection reconstruction algorithm, obtained the phantom’s two-dimensional image. Because of its low-energy deposition, Müller and Jerschow’s imaging technique may enable new application areas for magnetic resonance microscopy. Using already-developed methods, the researchers expect expansion to three-dimensional imaging to be straightforward.



The same detection scheme is applicable to NMR spectroscopy. Very delicate samples, such as explosives could be investigated with this method. Preliminary investigations also predict a sensitivity advantage over conventional experiments at length scales of millimeters to micrometers, which may be important in the measurement of NMR spectra within microfluidic devices.

Very strong magnetic fields, as generally required for MRI and NMR, can be avoided with the spin-noise detection scheme, making possible the development of extremely portable and minimally invasive MRI and NMR instruments.

James Devitt | EurekAlert!
Further information:
http://www.nyu.edu

More articles from Health and Medicine:

nachricht Antibiotic effective against drug-resistant bacteria in pediatric skin infections
17.02.2017 | University of California - San Diego

nachricht Tiny magnetic implant offers new drug delivery method
14.02.2017 | University of British Columbia

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Biocompatible 3-D tracking system has potential to improve robot-assisted surgery

17.02.2017 | Medical Engineering

Real-time MRI analysis powered by supercomputers

17.02.2017 | Medical Engineering

Antibiotic effective against drug-resistant bacteria in pediatric skin infections

17.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>