Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

NYU, Austrian researchers create non-invasive imaging method with advantages over conventional MRI

25.04.2006


New York University’s Alexej Jerschow, an assistant professor of chemistry, and Norbert Müller, a professor of chemistry at the University of Linz in Austria, have developed a completely non-invasive imaging method. Their work offers the benefits of magnetic resonance imaging (MRI) while eliminating patients’ exposure to irradiation and setting the stage for the creation of light, mobile MRI technology. The research, which appears in the latest issue of the Proceedings of the National Academy of Sciences (PNAS), was supported by the National Science Foundation.

MRI allows clinicians to non-invasively visualize soft tissue in the interior of the human body through the application of radiofrequency (rf) irradiation. However, the rf pulses of MRI machines deposit heat in patients and medical staff, though safety regulations that limit energy deposition have long been established. Jerschow and Müller have devised a low-energy, nuclear magnetic resonance (NMR) technique that does not require external rf-irradiation. Their technique, instead, relies on the detection of spontaneous, proton spin-noise in a tightly coupled rf-cavity.

In order to reconstruct spin-noise images that characterize MRI, the researchers used a commercial, liquid-state NMR spectrometer equipped with a cryogenically cooled probe. The sample, a phantom of four glass capillaries filled with mixtures of water and heavy water, remained at room temperature. The authors inserted the sample into a standard NMR tube and applied a magnetic field gradient to acquire spatial encoding information. They collected 30, one-dimensional images, and after applying a projection reconstruction algorithm, obtained the phantom’s two-dimensional image. Because of its low-energy deposition, Müller and Jerschow’s imaging technique may enable new application areas for magnetic resonance microscopy. Using already-developed methods, the researchers expect expansion to three-dimensional imaging to be straightforward.



The same detection scheme is applicable to NMR spectroscopy. Very delicate samples, such as explosives could be investigated with this method. Preliminary investigations also predict a sensitivity advantage over conventional experiments at length scales of millimeters to micrometers, which may be important in the measurement of NMR spectra within microfluidic devices.

Very strong magnetic fields, as generally required for MRI and NMR, can be avoided with the spin-noise detection scheme, making possible the development of extremely portable and minimally invasive MRI and NMR instruments.

James Devitt | EurekAlert!
Further information:
http://www.nyu.edu

More articles from Health and Medicine:

nachricht Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Study shines light on brain cells that coordinate movement

26.06.2017 | Life Sciences

Smooth propagation of spin waves using gold

26.06.2017 | Physics and Astronomy

Switchable DNA mini-machines store information

26.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>