A new target-seeking affibody molecule can be used to visualize cancer tumors and to treat them. This has been shown in a dissertation by Ann-Charlott Steffen to be publicly defended at Uppsala University on April 22.
The gamma camera image shows the distribution of radioactivity in a mouse given target-seeking affibody molecules marked with radioactivity. The uptake can be seen in the thyroid gland, the kidneys, and the tumor.
Every third Swede is estimated to receive a cancer diagnosis sometime in their lives, and nearly one Swede in four dies as a result of the disease. The need for improved detection and treatment of the disease is great.
Existing treatments include surgery, chemotherapy, and radiation. Surgery is most effective for large, well-defined tumors, but if the disease has spread, chemotherapy and/or radiation are needed. These forms of treatment affect all dividing cells, leading to toxic effects on healthy tissue. This toxicity limits the size of the dose that can be given, thereby also limiting the probability that the disease will be cured. By seeking out tumor cells and selectively delivering cytostatics or radiation to the cancer cells, the dose affecting healthy tissue can be reduced and the dose to the tumor can be increased. This improves the chances of curing the disease.
Linda Nohrstedt | alfa
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Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
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