A new target-seeking affibody molecule can be used to visualize cancer tumors and to treat them. This has been shown in a dissertation by Ann-Charlott Steffen to be publicly defended at Uppsala University on April 22.
The gamma camera image shows the distribution of radioactivity in a mouse given target-seeking affibody molecules marked with radioactivity. The uptake can be seen in the thyroid gland, the kidneys, and the tumor.
Every third Swede is estimated to receive a cancer diagnosis sometime in their lives, and nearly one Swede in four dies as a result of the disease. The need for improved detection and treatment of the disease is great.
Existing treatments include surgery, chemotherapy, and radiation. Surgery is most effective for large, well-defined tumors, but if the disease has spread, chemotherapy and/or radiation are needed. These forms of treatment affect all dividing cells, leading to toxic effects on healthy tissue. This toxicity limits the size of the dose that can be given, thereby also limiting the probability that the disease will be cured. By seeking out tumor cells and selectively delivering cytostatics or radiation to the cancer cells, the dose affecting healthy tissue can be reduced and the dose to the tumor can be increased. This improves the chances of curing the disease.
Linda Nohrstedt | alfa
The end of pneumonia? New vaccine offers hope
23.10.2017 | University at Buffalo
Scientists track ovarian cancers to site of origin: Fallopian tubes
23.10.2017 | Johns Hopkins Medicine
Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
23.10.2017 | Event News
17.10.2017 | Event News
10.10.2017 | Event News
23.10.2017 | Life Sciences
23.10.2017 | Physics and Astronomy
23.10.2017 | Health and Medicine