People with type 2 diabetes have highly acidic urine, a metabolic feature that explains their greater risk for developing uric-acid kidney stones, researchers at UT Southwestern Medical Center have found.
The study – the first to compare the urinary biochemical characteristics of type 2 diabetics with those of normal volunteers – is available online and will be published in the May issue of the Journal of the American Society of Nephrology.
Individuals with type 2 diabetes (non-insulin dependent diabetes mellitus) are at increased risk for developing kidney stones in general, and have a particular risk for uric-acid stones. The mechanisms for this greater risk were previously not entirely understood. This new study demonstrates that the propensity for type 2 diabetics to develop uric-acid stones is elevated because their urine is highly acidic.
Connie Piloto | EurekAlert!
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