Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Topical Antiseptic Reduces Umbilical Cord Infection and Mortality Risk

24.03.2006


Dry Umbilical Cord Care in Developing Countries Should Be Reconsidered



A topical antiseptic reduces umbilical cord infections and infant mortality risk, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health. In a study conducted in southern Nepal, babies who received umbilical cord cleanings after their cords were cut with chlorhexidine, a topical antiseptic, were 75 percent less likely to experience severe infections of their umbilical cord and were 24 percent less likely to die, as compared to a group of babies who received dry-cord care. When the cleansing of the cord was initiated within 24 hours of birth, mortality risk was reduced by 34 percent. The study is published in the March 18, 2006, edition of The Lancet.

In developing countries, many babies are born at home with the help of untrained attendants. While long-standing societal beliefs and practices play an important role in cord care, some traditional practices may introduce harmful pathogens to babies, which increases their risk of infection and death, explained Luke C. Mullany, PhD, MHS, lead author of the study and an assistant scientist in the Bloomberg School of Public Health’s Department of International Health. “When the cord cleansing with chlorhexidine was started soon after birth, the risk of death fell by more than one-third. The bottom line is that this is an extremely simple and inexpensive—just pennies per baby—way to significantly reduce infant mortality in developing countries. Combined with education about the cord, the antiseptic can easily be applied to newborn children at home by their parents.”


The Nepal Nutrition Intervention Project, Sarlahi, enrolled over 15,000 newborn infants from communities in southern Nepal between November 2002 and March 2005. One-third of the infants’ umbilical cords were treated with chlorhexidine, one-third with soap and water and one-third were left dry. Soap and water did not reduce infection or mortality risk. The infants who received chlorhexidine, however, were 75 percent less likely to have umbilical cord infection and their neonatal mortality was decreased by 24 percent as compared to the dry-cord care group.

"Our study findings suggest that current recommendations for dry-cord care be reconsidered. The World Health Organization recommends dry-cord care for babies born in developing countries, but does note that antiseptics might benefit infants born in areas where tradition calls for the application of harmful substances, such as animal feces or mud,” said James M. Tielsch, PhD, MHS, senior author of the study and a professor of international health at the Bloomberg School of Public Health.

Additional study authors from the Bloomberg School of Public Health are Gary L. Darmstadt, Joanne Katz and Steven C. LeClerq. Subarna K. Khatry, Shardaram Shrestha and Ramesh Adhikari also coauthored the study.

The study was supported by grants from the National Institutes of Health’s National Institute of Child Health & Human Development, The Bill & Melinda Gates Foundation and the United States Agency for International Development.

Kenna L. Lowe | EurekAlert!
Further information:
http://www.jhsph.edu

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>