We are closer to finding the missing 80% of breast cancer genes than ever before thanks to the success of the COSMIC database (Catalogue Of Somatic Mutations In Cancer) the 5th European Breast Cancer Conference (EBCC-5) was told today.
The genes BRCA1 and BRCA2 account for approximately 20% of the familial risk of breast cancer, leaving 80% to be explained. The COSMIC database developed at the Sanger Institute, Cambridge, UK was created in 2004 to provide free up to the minute genetic data to scientific communities and to prevent the duplication of research. The data in COSMIC has expanded to include data on 538 genes, 124,367 tumours with 23,157 mutations.
So far in genetic research 350 cancer genes have been identified and of these, 311 have a mutation in the somatic cell. Scientists believe that many somatic mutations are caused by a number of things – the way that DNA repairs and maintains itself, or past exposure to a harmful substance such as a virus. Alternatively it may be a combination of both.
EBCC-5 Press Office | alfa
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On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...
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The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
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