Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Mayo Clinic noninvasive test for heart disease risk

22.02.2006


"About 40 percent of the American public is considered to be at moderate risk for heart disease," says Iftikhar Kullo, M.D., of Mayo Clinic, the lead author of the study. "Nearly half the heart attacks come without warning, which means we need to do a better job of screening people. This test has that potential."



The test, aortic pulse wave velocity (aPWV), measures how fast the pulse wave travels down the aorta, the major artery arising from the heart. It is a potential screening tool because it is quick (takes 10-15 minutes), painless, noninvasive and likely to be less expensive compared with other cardiac screening tests, Dr. Kullo says. For the test, the patient lies on a bed and a pencil-like device (tonometer) is placed on the skin over the carotid artery (in the neck) and then the femoral artery (in the upper thigh). The tonometer measures the pressure wave inside the artery, and the information is fed into a computer for calculation of aPWV. A slower pulse wave means the artery is more elastic and healthier; a faster wave means the artery is stiffer and less healthy, he says.

The research found that study participants with stiffer arteries also had a greater presence and amount of calcium in the coronary arteries, an indicator of coronary atherosclerosis (plaque buildup). Previous research showed aPWV predicts cardiovascular disease in older adults, but the association of aPWV and the amount of coronary artery calcium (CAC) in the general population has been unknown, Dr. Kullo says.


The association between artery stiffness and CAC strengthens the case for using aPWV as a screening tool, such as in adults with moderate risk, those with a family history of heart disease, patients with high blood pressure, and those with kidney disease, Dr. Kullo says.

Researchers tested 401 participants (213 men and 188 women) between the ages of 32 and 84 -- none with a history of heart attack or stroke -- for the community-based research between 2002 and 2004. The median age was 60. This research also discovered a significant interaction between aPWV and smoking history; the association between aPWV and the presence and quantity of CAC was stronger in smokers than in nonsmokers, he says.

Traci Klein | EurekAlert!
Further information:
http://www.mayo.edu

More articles from Health and Medicine:

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

Im Focus: Computer-Designed Customized Regenerative Heart Valves

Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.

Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...

Im Focus: Light-induced superconductivity under high pressure

A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.

Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Supersonic waves may help electronics beat the heat

18.05.2018 | Power and Electrical Engineering

Keeping a Close Eye on Ice Loss

18.05.2018 | Information Technology

CrowdWater: An App for Flood Research

18.05.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>