Intakes of dietary or supplemental antioxidants were not associated with a decreased risk of prostate cancer among men in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, according to a study in the February 15 issue of the Journal of the National Cancer Institute . The study did find that vitamin E and beta-carotene supplementation may be associated with reduced prostate cancer risk in certain population subgroups.
Research suggests that micronutrients such as vitamin E, vitamin C, and carotenoids may play a role in preventing cancer development because of their ability to combat free radicals, agents that can damage cellular DNA, lipid membranes, and proteins. In many studies, vitamin E has been associated with a reduced risk of prostate cancer, and beta-carotene has been associated with increased lung cancer risk in previous studies. However, no studies have examined associations between intakes of these three antioxidant micronutrients and the risk of prostate cancer.
Richard B. Hayes, Ph.D., at the National Cancer Institute, and colleagues assessed the risk of prostate cancer for 29,361 men ages 55 to 74 enrolled in the PLCO Cancer Screening Trial, based on their daily intake of beta-carotene, vitamin E, and vitamin C. The researchers looked at intake of antioxidants from both dietary sources and from supplements.
Ariel Whitworth | EurekAlert!
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