Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Phytoestrogen-rich foods protect against cancer

14.02.2006


Men who have a diet rich in soya products, beans and sunflower seeds run a much lower risk of contracting prostate cancer. New findings from Karolinska Institutet show that foods rich in phytoestrogens – plant-produced oestrogens – protect against the most common form of cancer in the western world.



Some 10,000 men develop prostate cancer in Sweden each year. Just why prostate cancer is so common is still something of a mystery, but age, ethnicity and genes are usually considered risk factors. However, several studies also show that diet also has an important part to play. Recently, scientists have become interested in the protective effect of oestrogen-like compounds in plants, or phytoestrogens. In countries like China and Japan, people ingest more of these compounds than in the west, and the incidence of prostate cancer is lower. Phytoestrogens are usually divided into two groups: lignans and isoflavones, the former being found mainly in linseed, rye, berries and vegetables, the latter in soya beans.

Scientists at Karolinska Institutet’s Department of Medical Epidemiology and Biostatistics have studied the correlation between prostate cancer and phytoestrogen in a large population-based case-control study. Involving 1,499 patients between the ages of 35 and 79 with recently diagnosed prostate cancer, it is the largest study of its kind on a western population. 1,130 healthy controls were identified through a process of matching by age and place of residence. All participants were asked to complete a questionnaire about their dietary habits and to take a blood test. A smaller group (209 cases and 214 controls) had the amount of the phytoestrogen enterolactone in their blood measured.


The study shows that men who had a high intake of phytoestrogen-rich food, such as beans (which offered the greatest protection), soya products, linseed, sunflower seeds, berries and peanuts, ran a 26 per cent lower risk of developing prostate cancer. We also found that men with very low blood levels of enterolactone had a greater chance of contracting the disease.

The intake of lignans matches closely that of other western countries, the richest sources being linseed, rye bread, wheat bread, and berries. The intake was low, which can be expected as soya products are not so common in Sweden. In China, where soya beans are much more popular, one study revealed a thousand-fold higher isoflavanoid intake than in our study.

The protective effect might derive directly from the phytoestrogens alone or in combination with other substances found in the same type of food. We do not, however, recommend the intake of artificial phytoestrogen supplements, as the tablets have not been clinically tested; they also contain high concentrations and can have adverse side-effects.

The results of the study shed light on the intake of phytoestrogens in Sweden. This can be of guidance in studies of other cancer forms that the compounds can be thought to affect. The study also brings us closer to preventative measures and future treatments. Using the genetic information gathered, we will go on to study if there is an interaction between the intake of phytoestrogens from the diet and variations of certain genes in the population that influence the risk of contracting prostate cancer.

| alfa
Further information:
http://www.ki.se

More articles from Health and Medicine:

nachricht Cardiac diseases: when less is more
30.03.2017 | Universitätsspital Bern

nachricht TSRI researchers develop new method to 'fingerprint' HIV
29.03.2017 | Scripps Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Researchers shoot for success with simulations of laser pulse-material interactions

29.03.2017 | Materials Sciences

Igniting a solar flare in the corona with lower-atmosphere kindling

29.03.2017 | Physics and Astronomy

As sea level rises, much of Honolulu and Waikiki vulnerable to groundwater inundation

29.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>