Aussie of the Year announces new vaccine trial
The technology used in the worlds first cervical cancer vaccine will be tweaked to fight the most common sexually transmitted disease, genital warts.
Australian of the Year and University of Queensland (UQ) cervical cancer vaccine creator Professor Ian Frazer launched a therapeutic vaccine trial for genital warts today (Tuesday, February 7).
Patients from Brisbane and China will take part in the joint project for UQs cancer research centre, the Centre for Immunology and Cancer Research (CICR) and the hospitals sexual health service, Princess Alexandra Sexual Health (PASH).
Professor Frazer said the vaccine used virus-like particles to deliver an antigen (protein that produces immunity) for genital warts similar to the cervical cancer vaccine.
"It will target the main causes of visible genital warts which are human papillomavirus (HPV6) and (HPV11)," Dr Frazer said.
A pilot study of vaccine CICRVAX6 by UQs Chinese research partner, Wenzhou Medical College, showed the vaccine was potentially effective at treating genital warts in humans.
Now PASH is running a larger trial and needs 120 men and 120 women who have recurring genital warts.
Participants must be aged between 18 and 65 years, should not be pregnant or immunosuppressed and will be required for seven medical visits, with their travel costs refunded.
Trial Manager and PASH Senior Medical Officer Dr David Jardine said patients would receive standard treatment for genital warts and two vaccine shots, which are saline solutions injected in the upper arm, over two months.
"The incentives for people are that they get free consultations, free treatment, free vaccines and their travelling expenses paid," Dr Jardine said.
He said conventional wart treatments of freezing, burning or painting visible warts with acid might not switch off the active infection.
The 18-month trial will be launched in conjunction with Wartfest, an annual expo about new developments and treatments for warts, HPV and cancer, featuring expert speakers from Australia and Canada.
Genital warts are transmitted by skin contact and the 2003 Australian Study of Sex and Relationships of 20,000 adults revealed four percent of people had had visible genital warts.
Professor Frazer said developing a preventative warts vaccine or a combined vaccine for cervical cancer and genital warts was one of the next steps if the therapeutic trial was successful.
Miguel Holland | EurekAlert!
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...