Treatment with target-seeking antibodies reduces growth in certain tumor cells and does so in a different way than with ordinary radiation therapy. This is shown by David Eriksson in a new dissertation at Umeå University in Sweden.
Tumor diseases can be treated with surgery, radiation, or chemotherapy. A new type of treatment that makes use of the antibodies with radioactive substances attached has attracted more and more interest. When the antibodies are injected they have the capacity to wander around in the blood circulation and actively attract tumors to them. In other words, they are target-seeking antibodies. They can even find tumors that have not grown large enough to be detected by other methods. When the antibody binds to the tumor, the radioactive substance can deliver local radiation for a long time.
The dissertation shows that this type of cancer treatment, “radioimmune therapy,” can provide substantial inhibition of tumor cell growth. However, the operative mechanism is not the same as in ordinary radiation treatment. In this case the low-dose radiation is emitted over a long period and activates parts of the cell’s defense system, which makes cells temporarily stop dividing in order to repair any damage from the radiation. If this doesn’t succeed, then the cells will try to multiply with damaged genes, which results in “cell division disasters” and ultimate activation of the “suicide programs” that make the tumor cells die of their own accord. These new methods of treatment are seen as having great potential and have already been put to use for certain tumor diseases.
Hans Fällman | alfa
Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan
Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
21.02.2017 | Earth Sciences
21.02.2017 | Medical Engineering
21.02.2017 | Trade Fair News