Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Controlling neglected tropical diseases will boost fight against HIV, TB, and malaria

31.01.2006


A press briefing will take place at the Nobel Forum, Stockholm, at 6.15pm local time on Monday 30th January 2006. If you would like to attend, please contact Katarina Sternudd (Karolkinska Institutet) or Clare Oh (Earth Institute)--see contact details below.



Achieving success in the global fight against the "big three" diseases--HIV/AIDS, tuberculosis and malaria, which together account for 5.6 million deaths a year--may well require a concurrent attack on the world’s most neglected tropical diseases, says a team of researchers in the international open access journal PLoS Medicine.

The team will present its work at a meeting on malaria and the neglected tropical diseases at the Nobel Forum, Stockholm, on 30-31 January 2006, organized by the UN Millennium Project and hosted by Karolinska Institutet and the Nobel Forum.


The neglected tropical diseases, such as leprosy and sleeping sickness, are disabling infectious diseases (mostly due to parasites) affecting the world’s poorest people. The research team--Peter Hotez (Principal Investigator, Human Hookworm Vaccine Initiative), David Molyneux and Eric Ottesen (Global Alliance to Eliminate Lymphatic Filariasis), Alan Fenwick (Schistosomiasis Control Initiative), Jeffrey Sachs (Director of the UN Millennium Project and of the Earth Institute at Columbia University) and Sonia Sachs (Millennium Village Project)--argues that initiatives for tackling the big three would be far more effective if they also included control of the neglected tropical diseases.

"The evidence indicates that coinfection with one or more neglected tropical disease may profoundly affect the outcome of one or more of the big three," says the team. For example, people with HIV infection or TB who are also infected with helminth infections, such as hookworm and schistosomiasis, have a worse prognosis. There is also emerging evidence that people infected with the neglected tropical diseases are more susceptible to becoming infected with the big three.

In addition to these interactions, it is becoming clear that there is extensive geographic overlap between the big three and the neglected tropical diseases. "HIV/AIDS, TB, and malaria occur predominantly in populations who are polyparasitized," say Professor Hotez and colleagues. The public health community, they argue, must therefore begin to integrate neglected disease control with its worldwide efforts to tackle HIV, TB, and malaria.

"The neglected tropical diseases," they say, "must now join the big three to create a 21st century ’gang of four.’ For too long, the public health community has been tackling each of these diseases in isolation."

It would cost just 40 cents per person per year--a total of just US$200 million annually--to deliver a package of four drugs to about 500 million Africans, which would control or eliminate seven neglected tropical diseases. "Given the compelling logic and the very modest costs of embracing neglected tropical disease control efforts," say the authors, "it is surprising that those aiming to control the big three have largely ignored these opportunities."

Paul Ocampo | EurekAlert!
Further information:
http://www.plos.org
http://www.plosmedicine.org

More articles from Health and Medicine:

nachricht New malaria analysis method reveals disease severity in minutes
14.08.2017 | University of British Columbia

nachricht New type of blood cells work as indicators of autoimmunity
14.08.2017 | Instituto de Medicina Molecular

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

Im Focus: Scientists improve forecast of increasing hazard on Ecuadorian volcano

Researchers from the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science, the Italian Space Agency (ASI), and the Instituto Geofisico--Escuela Politecnica Nacional (IGEPN) of Ecuador, showed an increasing volcanic danger on Cotopaxi in Ecuador using a powerful technique known as Interferometric Synthetic Aperture Radar (InSAR).

The Andes region in which Cotopaxi volcano is located is known to contain some of the world's most serious volcanic hazard. A mid- to large-size eruption has...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

New thruster design increases efficiency for future spaceflight

16.08.2017 | Physics and Astronomy

Transporting spin: A graphene and boron nitride heterostructure creates large spin signals

16.08.2017 | Materials Sciences

A new method for the 3-D printing of living tissues

16.08.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>