Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Test identifies best candidates for implanted cardiac defibrillator, screens out those not helped

30.01.2006


Study shows one third of candidates are unlikely to benefit from ICD



Last year, about 170,000 people in North America had devices surgically implanted to stop potentially fatal arrhythmias. For many, these were life-saving, but for others they were unnecessary, uncomfortable, and sometimes dangerous. Now a new, noninvasive test may help determine which patients are most likely to benefit from the device, known as implantable cardiac defibrillator (ICD). A large, multicenter, NIH-sponsored study coordinated by Columbia University Medical Center researchers reported on the accuracy of the test was and was published in the latest issue of the Journal of the American College of Cardiology.

The test, known as the Microvolt T-wave Alternans (MTWA) test, measures the electrical activity in the heart while the patient is performing light exercise on a stationary bicycle or treadmill. It can detect an electrical signal that can identify a heart likely to generate a life-threatening rhythm disturbance, a signal too slight to be detected by the traditional electrocardiogram (ECG). The MWTA test will be most helpful for patients who are at risk but have not yet had a cardiac arrest. If an arrhythmia occurred in a patient who had an ICD, the device would deliver a pulse of electrical current through the heart in order to stop the potentially fatal arrhythmia.


"Until now, it’s been difficult to determine which patients need prophylactic ICDs and which are unlikely to be helped by them, but this noninvasive and inexpensive office-based test can identify up to a third of candidates for the devices who are not likely to benefit from them," said J. Thomas Bigger, MD, professor of medicine and of pharmacology at Columbia University Medical Center, who conducted the research.

The study followed 549 patients from 11 North American clinical centers for two years following an MWTA test.

The MTWA test might also reduce healthcare expenses, since ICD implantation costs roughly $50,000 and the test costs about $400. But as doctors become more confident about accurately targeting which patients would be helped by the devices, the number of prophylactic implantations may increase.

The test does not have national coverage by Medicare intermediaries, but the Centers for Medicare and Medicaid Services (CMS) is currently reviewing its coverage policy for the MTWA test and is expected to make a decision on coverage in March.

Craig LeMoult | EurekAlert!
Further information:
http://www.columbia.edu
http://www.cumc.columbia.edu

More articles from Health and Medicine:

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

nachricht The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>