Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Use your brain, halve your risk of dementia

26.01.2006


Research from UNSW provides the most convincing evidence to date that complex mental activity across people’s lives significantly reduces the risk of dementia. The researchers found that such activity almost halves the incidence of dementia.



The paper, which has just been published in Psychological Medicine, is the first comprehensive review of the research in the field of ’brain reserve’, which looks at the role of education, occupational complexity and mentally stimulating lifestyle pursuits in preventing cognitive decline. The paper integrates data from 29,000 individuals across 22 studies from around the world.

"Until now there have been mixed messages about the role of education, occupation, IQ and mentally stimulating leisure activities, in preventing cognitive decline. Now the results are much clearer," said the lead author, Dr Michael Valenzuela, from the School of Psychiatry at UNSW. "It is a case of ’use it or lose it’. If you increase your brain reserve over your lifetime, you seem to lessen the risk of Alzheimer’s and other neurodegenerative diseases."


The key conclusion is that individuals with high brain reserve have a 46 percent decreased risk of dementia, compared to those with low brain reserve. All the studies assessed agreed that mentally stimulating leisure activities, even in late life, are associated with a protective effect.

"This suggests that brain reserve is not a static property, nor that it is determined by early life experiences such as level of education, socio-economic deprivation or poor nutrition," said Dr Valenzuela. "It is never too late to build brain reserve."

Dr Valenzuela’s previous research showed that after five weeks of memory-based mental exercise, participants increased brain chemistry markers in the opposite direction to that seen in Alzheimer’s disease. "The interesting point here is that this change was concentrated to the hippocampus, a part of the brain first affected in dementia," said Dr Valenzuela.

This is consistent with studies of brain reserve in mice, where some of the animals were ’hothoused’ in stimulating environments. These mice had changes in the microstructure of their brains, compared with the controls.

"We now need a clinical trial to improve our neurobiological understanding of the brain-reserve effect in humans," said Dr Valenzuela. "Perhaps this could be based around mentally stimulating leisure activities that are fun."

The co-author of the paper is Professor Permider Sachdev, also from the School of Psychiatry at UNSW, who is based at The Neuropsychiatric Institute at the Prince of Wales Hospital.

Contact details: Susi Hamilton, UNSW Media unit, tel. 9385 1583 or 0422 934 024

Susi Hamilton | EurekAlert!
Further information:
http://www.unsw.edu.au

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Rapid environmental change makes species more vulnerable to extinction

19.10.2017 | Life Sciences

Integrated lab-on-a-chip uses smartphone to quickly detect multiple pathogens

19.10.2017 | Interdisciplinary Research

Fossil coral reefs show sea level rose in bursts during last warming

19.10.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>