Risks of sulfonylurea drugs in the treatment of diabetes mellitus

Sulfonylurea drugs, used in the treatment of patients with diabetes mellitus to lower blood sugar levels, have been suspected since the 1970s of increasing cardiovascular mortality as well.

In this careful study, some 5800 patients treated with pills for their diabetes were monitored for an average of about 5 years. Patients who were prescribed a sulfonylurea drug (chlorpropamide, tolbutamide or glyburide) experienced higher mortality rates than those who received metformin. Mortality from all causes and deaths attributable to heart attacks were both higher among patients taking sulfonylureas. Patients taking higher doses and those with better prescription compliance were more likely to die than those prescribed lower doses or who took less of their medication.

All latest news from the category: Health and Medicine

This subject area encompasses research and studies in the field of human medicine.

Among the wide-ranging list of topics covered here are anesthesiology, anatomy, surgery, human genetics, hygiene and environmental medicine, internal medicine, neurology, pharmacology, physiology, urology and dental medicine.

Back to home

Comments (0)

Write a comment

Newest articles

The Sound of the Perfect Coating

Fraunhofer IWS Transfers Laser-based Sound Analysis of Surfaces into Industrial Practice with “LAwave”. Sound waves can reveal surface properties. Parameters such as surface or coating quality of components can be…

Customized silicon chips

…from Saxony for material characterization of printed electronics. How efficient are new materials? Does changing the properties lead to better conductivity? The Fraunhofer Institute for Photonic Microsystems IPMS develops and…

Acetylation: a Time-Keeper of glucocorticoid Sensitivity

Understanding the regulatory mechanism paves the way to enhance the effectiveness of anti-inflammatory therapies and to develop strategies to counteract the negative effects of stress- and age-related cortisol excess. The…

Partners & Sponsors