Specialists of the Gamalei Research Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, and the Botkin Clinical Hospital have developed the method that allows to significantly simplify examination of patients suffering from stomach and duodenal diseases caused by the Helicobacter pylori bacteria. The researchers have created immunological test-system capable to discover the pathogene toxin in the patients’ saliva and faeces without resorting to traditional complicated and expensive diagnostics methods.
Stomach and duodenal ulcers are often of bacterial nature. The ulser pathogene, the Helicobacter pylori bacterium, is dangerous by its cytotoxin, in the presence of which the ulcer more often develops into a malignant form. The contemporary medicine possesses a lot of sensitive methods for diagnostics of bacteria and their proteins, but, unfortunately, many of them are complicated and expensive. The majority of methods require penetration into the stomach or the duodenum, thus they are not always suitable for examination of children and bad cases. The necessity for a simplier examination method is obviously imminent.
Physicians suggest to use diagnostic antiserum to VacA toxin protein for simplified diagnostics of Helicobacteriosis. The researchers have cloned a small tail fragment of this protein’s gene. The gene worked duly in the E. coli and produced the protein in the quantities sufficient for immunization. Rabbits were immunized by the purified protein, and serum specific for Helicobacter cytotoxin was produced from their blood. The test-system was tried on real clinical material – saliva and faeces samples of chronic invalids during various exacerbation periods, and before the deiseas and after the conducted treatment.
Sergey Komarov | alfa
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A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
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In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
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The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
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