Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Screening chest x-ray detects early-stage lung cancers at high rates, study results show

21.12.2005


Almost half of lung cancers detected by a chest x-ray were early-stage cancers, according to baseline results of a large, randomized clinical trial that is testing the efficacy of a chest x-ray as a screening test for lung cancer. The study results are published in the December 21 issue of the Journal of the National Cancer Institute.



Lung cancer causes one million deaths worldwide every year. When patients begin to experience symptoms of lung cancer, the cancers are often advanced and treatment is rarely successful; 90% of newly diagnosed lung cancer patients die within 2 years of diagnosis.

In 1992, The National Cancer Institute launched the still-ongoing Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial to evaluate screening tests for each of the four cancers. The PLCO Cancer Screening Trial is the largest trial ever conducted in the United States. The 155,000 men and women enrolled in the study were asked about past and present smoking habits, medical history of themselves and their families, and personal characteristics. For the lung cancer portion of the trial, participants were randomly assigned to a control group or to a screening group that received a single-view, posterior–anterior chest x-ray.


According to the baseline results of the 77,465 patients in the screening group, reported by Martin M. Oken, M.D., of the Hubert H. Humphrey Cancer Center in Robbinsdale, Minn., and colleagues from the PLCO Project Team, 5991 (8.9%) participants had a test result that was suspicious for cancer, and after further follow-up and medical tests, 126 participants were diagnosed with lung cancer. Forty-four percent of the cancers found were diagnosed as stage I cancers. Chest x-ray detected 6.3 lung cancers per 1000 current smokers, 4.9 lung cancers per 1000 former smokers who had smoked in the past 15 years, 1.1 lung cancers per 1000 former smokers who had not smoked within the past 15 years, and 0.4 lung cancers per 1000 never-smokers. Chest x-ray found cancer at a higher rate in men than in women.

"The data suggest a high rate of early detection and possibly important differences between screening for lung cancer in women and in men," write the authors. "The answer to the important question of reduction in lung cancer mortality must await analysis of the two study arms as these data mature."

Ariel Whitworth | EurekAlert!
Further information:
http://www.oxfordjournals.org
http://www.northmemorial.com
http://jncicancerspectrum.oxfordjournals.org/

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>