Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Screening chest x-ray detects early-stage lung cancers at high rates, study results show

21.12.2005


Almost half of lung cancers detected by a chest x-ray were early-stage cancers, according to baseline results of a large, randomized clinical trial that is testing the efficacy of a chest x-ray as a screening test for lung cancer. The study results are published in the December 21 issue of the Journal of the National Cancer Institute.



Lung cancer causes one million deaths worldwide every year. When patients begin to experience symptoms of lung cancer, the cancers are often advanced and treatment is rarely successful; 90% of newly diagnosed lung cancer patients die within 2 years of diagnosis.

In 1992, The National Cancer Institute launched the still-ongoing Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial to evaluate screening tests for each of the four cancers. The PLCO Cancer Screening Trial is the largest trial ever conducted in the United States. The 155,000 men and women enrolled in the study were asked about past and present smoking habits, medical history of themselves and their families, and personal characteristics. For the lung cancer portion of the trial, participants were randomly assigned to a control group or to a screening group that received a single-view, posterior–anterior chest x-ray.


According to the baseline results of the 77,465 patients in the screening group, reported by Martin M. Oken, M.D., of the Hubert H. Humphrey Cancer Center in Robbinsdale, Minn., and colleagues from the PLCO Project Team, 5991 (8.9%) participants had a test result that was suspicious for cancer, and after further follow-up and medical tests, 126 participants were diagnosed with lung cancer. Forty-four percent of the cancers found were diagnosed as stage I cancers. Chest x-ray detected 6.3 lung cancers per 1000 current smokers, 4.9 lung cancers per 1000 former smokers who had smoked in the past 15 years, 1.1 lung cancers per 1000 former smokers who had not smoked within the past 15 years, and 0.4 lung cancers per 1000 never-smokers. Chest x-ray found cancer at a higher rate in men than in women.

"The data suggest a high rate of early detection and possibly important differences between screening for lung cancer in women and in men," write the authors. "The answer to the important question of reduction in lung cancer mortality must await analysis of the two study arms as these data mature."

Ariel Whitworth | EurekAlert!
Further information:
http://www.oxfordjournals.org
http://www.northmemorial.com
http://jncicancerspectrum.oxfordjournals.org/

More articles from Health and Medicine:

nachricht A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital

nachricht Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

Im Focus: Quantum-physical Model System

Computer-assisted methods aid Heidelberg physicists in reproducing experiment with ultracold atoms

Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...

Im Focus: Glacier bacteria’s contribution to carbon cycling

Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.

A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

New quantum liquid crystals may play role in future of computers

21.04.2017 | Physics and Astronomy

A promising target for kidney fibrosis

21.04.2017 | Health and Medicine

Light rays from a supernova bent by the curvature of space-time around a galaxy

21.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>