Research project to identify best ways of treating and preventing hospital superbugs
Researchers at The University of Nottingham are joining forces with health protection specialists to study the spread of hospital superbugs such as MRSA and identify successful methods of prevention and treatment.
The results of the research project could be used to inform future best practice guidance for hospitals and health professionals.
The three-year project is being carried out by Dr Phil ONeill in the Universitys School of Mathematical Sciences, Dr Ben Cooper and colleagues at the Health Protection Agency in London and University College London Hospitals, and is funded with £113,726 from the Wellcome Trust.
The researchers will use state-of-the-art computer technology and mathematical modelling to analyse data taken from hospitals where outbreaks have occurred.
Hospital-acquired infections represent a major threat to patient welfare and have a substantial financial impact on the National Health Service. Infections caused by antibiotic-resistant bacteria such as methicillin-resistant staphylococcus aureus (MRSA) are of particular concern because they are so difficult to treat.
In particular, the researchers are hoping to shed light on the effect of various antibiotics on a range of infections, the way in which different strains of infections work together, often causing infections to worsen, and the methods that are used to prevent and contain outbreaks.
Dr ONeill said: "The data that we have from the hospitals is exceptionally detailed, so we will be using sophisticated computational methods to extract the relevant information and analyse it.
"We believe our methods will be an improvement on the way in which this kind of information has been analysed in the past as it will allow us to look at how various factors interact with each other, which has previously been overlooked."
The type of data being analysed could include anything from information on the number of infected patients on a ward, the type of treatments and drugs they received and the results of swab tests to methods used to try to avoid or control infections, such as hygiene practices and isolating affected patients.
The researchers will be looking for patterns in the successful treatment and management of infections that could lead to new strategies for handling and preventing outbreaks.
Dr Phil O’Neill | alfa
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...