Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Imperial receives Gates Foundation grant to develop new tests for managing AIDS treatment in developing countries

22.11.2005


Imperial College London has received a £4.9 ($8.6) million grant from the Bill & Melinda Gates Foundation to develop a simple, affordable and rapid test to measure the health of the immune system in HIV/AIDS patients in developing countries.



The ‘CD4 Initiative’ will develop an easy to use device which can measure CD4+ T-lymphocytes in HIV+ patients. The CD4 cell count measures the number of these critical disease-fighting cells in the blood, a figure which health care workers need in order to make key clinical decisions in managing HIV disease, such as when to begin or to switch antiretroviral therapy.

Current technologies for measuring CD4 counts are expensive to buy and maintain, and require a level of infrastructure and training which is often not available in many developing countries. The CD4 Initiative will develop new tests that are more appropriate for these countries based on specifications developed with health care workers in hospitals and clinics in Africa and elsewhere in the developing world.


Professor Stephen Smith, Principal of the Faculty of Medicine at Imperial College London, said: “Despite the burden of HIV/AIDS on the developing world, many of the diagnostic tools are just not accessible there due to the high cost and complexity of use. This initiative will help develop new, simple, rapid, robust and affordable tools and help remove one important barrier to the effective implementation of AIDS care in these countries.”

The principal investigator, Dr. Hans George Batz, together with the Imperial-based team will manage an R&D programme to develop these much needed diagnostics. Dr. Batz is a former Senior Vice President of Research and Development at Roche Diagnostics and has been involved with the development of the initiative for the past two years. Dr. Batz will be supported by an international steering committee of experts, a small staff and the Imperial College’s liaison to the project, Dr. Wendy Ewart. The initiative will take a project management approach, common in industry, in which multiple research teams around the world from academia, private companies and other institutions will work collaboratively under the leadership of Dr. Batz and with strict milestones and timelines to achieve.

A Research Funding Agreement for interested test developers and researchers for the CD4 Initiative will be issued in spring 2006. Inquiries about the project can be made to cd4@icl.ac.uk.

Gregg Gonsalves, from Gay Men’s Health Crisis in New York City, and who was instrumental in the establishment of the initiative, praised the Bill & Melinda Gates Foundation and Imperial College: “The CD4 Initiative is providing a bold new solution to this key problem in public health by bringing together the know-how in product development from industry with the creativity of scientists from all quarters to bring a product to the field more quickly than could be done otherwise. Healthcare workers from developing countries have been clamouring for point-of-care assays for measuring CD4 counts for several years now as management of antiretroviral therapy is difficult without these tests. We are elated that Dr. Batz, Imperial College and the Bill & Melinda Gates Foundation are responding to these urgent pleas for help.”

Tony Stephenson | alfa
Further information:
http://www.imperial.ac.uk

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>