Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New tuberculosis test scoops top prize at Medical Futures competition

08.11.2005


An inexpensive and rapid test for tuberculosis (TB) which could be used in developing countries has won first place in the Best Innovation to Improve Global Healthcare category of the Medical Futures Innovation Awards. It also scooped the overall prize at the awards ceremony held last week in London.



The test, known as MODS (Microscopic Observation Drug Susceptible Assay) is able to confirm the presence of TB from sputum samples in one week on average, taking one third to one quarter of the time of a standard TB test. At the same time, the new test is able to spot if the TB is drug resistant which is five to ten times faster than existing tests. The test costs $2 to perform compared with around $30 to $40 for a standard test.

Dr David Moore, from Imperial College London, and the winner of the Award said: “This test can be carried out using cheap and readily available tools and requires relatively little training or expertise. This is particularly important in developing countries which may not have the infrastructure we take for granted in the developed world.”


Each year around 8 million new cases of TB are diagnosed, and 1.7 million people die from TB, often as a result of delayed diagnosis and through not being able to spot if the TB is drug resistant.

Working with colleagues from Peru’s National TB Programme, the Universidad Peruana Cayetano Heredia, AB PRISMA, and John Hopkins Bloomberg School of Public Health, the team realised many TB patients were dying unnecessarily largely due to an inability to cheaply and quickly diagnose TB. They have now completed proof of principle studies, evaluated the test in large-scale field trials, and are now looking at strategies for implementation and roll-out to optimize impact and cost-effectiveness.

Professor Jon Friedland, from Imperial College London, who helped develop the test, added: “TB is a major cause of mortality in the developing world, and eradicating it has been made difficult through a lack of inexpensive diagnosis equipment which can be deployed quickly and easily. The MODS test provides a simple solution to this, and I am very pleased that this has been acknowledged by winning this very prestigious award.”

Professor Stephen Smith, Principal of the Faculty of Medicine at Imperial College London said: “David and Jon’s work is an excellent example of how organisations such as Imperial can really help make a difference. The development of a low cost practical solution which can be rolled out in countries with a limited infrastructure could make an enormous difference in eradicating TB.”

The work was funded by the Wellcome Trust.

Tony Stephenson | alfa
Further information:
http://www.imperial.ac.uk

More articles from Health and Medicine:

nachricht Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center

nachricht Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Rainbow colors reveal cell history: Uncovering β-cell heterogeneity

22.09.2017 | Life Sciences

Penn first in world to treat patient with new radiation technology

22.09.2017 | Medical Engineering

Calculating quietness

22.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>