Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Advice on chickenpox needs urgent review says DTB

04.11.2005


The UK’s Drug and Therapeutics Bulletin (DTB), published by Which?, has identified an important error in standard guidelines on fetal varicella syndrome. This finding has major implications worldwide for advice given to women with chickenpox in late pregnancy.



Fetal varicella syndrome is an uncommon but potentially fatal condition that can affect the unborn child of a pregnant woman who catches chickenpox. It can cause problems such as skin loss or scarring, under-development or weakness of limbs and low birth weight.

National guidelines in, for example, the UK, USA, Ireland, New Zealand, Holland and Spain, have suggested that the risk of fetal varicella syndrome is confined to maternal chickenpox infection in the first 20 weeks of pregnancy. However, DTB has reported evidence that undermines this view, as do guidelines in Australia and Canada.


Recently published data have estimated the risk of fetal varicella syndrome in children exposed to chickenpox in the uterus at around 0.5 per cent after maternal infection at between two and 12 weeks of pregnancy; 1.4 per cent after infection at 12-28 weeks; and 0 per cent from 28 weeks onwards.1

These data are based on a recently published collation of evidence.2 Crucially, this collation includes a study that reported a case of fetal varicella syndrome following maternal infection at 24 weeks of pregnancy (in a total of 157 women infected after 20 weeks).3 The collation also included eight other published cases, from various countries, of fetal varicella syndrome where the mother was infected after the 20th week of pregnancy.4-11 There has also been a recently reported case, in France, of the syndrome after maternal infection in the 22nd week of pregnancy.12

In view of this evidence, DTB is urging advisory bodies worldwide to review their advice on the risk of fetal varicella syndrome. Already, in the UK, the Department of Health, Royal College of Obstetricians and Health Protection Agency have said they will be amending their guidance in response to DTB’s call for such action. Their advice will now reflect evidence that fetal varicella syndrome can occur following maternal chickenpox infection in the second half of pregnancy.

Dr Ike Iheanacho, editor, DTB, said:

“Guidance suggesting that fetal varicella syndrome can only occur in the first 20 weeks of pregnancy is at odds with published evidence.

“Such advice therefore needs to be revised worldwide as a matter of urgency. Until this happens, parents and healthcare professionals will be misinformed about an uncommon but highly dangerous complication of chickenpox infection in pregnancy.”

John Cox | alfa
Further information:
http://www.dtb.org.uk
http://www.which.co.uk

More articles from Health and Medicine:

nachricht Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>