Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Advice on chickenpox needs urgent review says DTB

04.11.2005


The UK’s Drug and Therapeutics Bulletin (DTB), published by Which?, has identified an important error in standard guidelines on fetal varicella syndrome. This finding has major implications worldwide for advice given to women with chickenpox in late pregnancy.



Fetal varicella syndrome is an uncommon but potentially fatal condition that can affect the unborn child of a pregnant woman who catches chickenpox. It can cause problems such as skin loss or scarring, under-development or weakness of limbs and low birth weight.

National guidelines in, for example, the UK, USA, Ireland, New Zealand, Holland and Spain, have suggested that the risk of fetal varicella syndrome is confined to maternal chickenpox infection in the first 20 weeks of pregnancy. However, DTB has reported evidence that undermines this view, as do guidelines in Australia and Canada.


Recently published data have estimated the risk of fetal varicella syndrome in children exposed to chickenpox in the uterus at around 0.5 per cent after maternal infection at between two and 12 weeks of pregnancy; 1.4 per cent after infection at 12-28 weeks; and 0 per cent from 28 weeks onwards.1

These data are based on a recently published collation of evidence.2 Crucially, this collation includes a study that reported a case of fetal varicella syndrome following maternal infection at 24 weeks of pregnancy (in a total of 157 women infected after 20 weeks).3 The collation also included eight other published cases, from various countries, of fetal varicella syndrome where the mother was infected after the 20th week of pregnancy.4-11 There has also been a recently reported case, in France, of the syndrome after maternal infection in the 22nd week of pregnancy.12

In view of this evidence, DTB is urging advisory bodies worldwide to review their advice on the risk of fetal varicella syndrome. Already, in the UK, the Department of Health, Royal College of Obstetricians and Health Protection Agency have said they will be amending their guidance in response to DTB’s call for such action. Their advice will now reflect evidence that fetal varicella syndrome can occur following maternal chickenpox infection in the second half of pregnancy.

Dr Ike Iheanacho, editor, DTB, said:

“Guidance suggesting that fetal varicella syndrome can only occur in the first 20 weeks of pregnancy is at odds with published evidence.

“Such advice therefore needs to be revised worldwide as a matter of urgency. Until this happens, parents and healthcare professionals will be misinformed about an uncommon but highly dangerous complication of chickenpox infection in pregnancy.”

John Cox | alfa
Further information:
http://www.dtb.org.uk
http://www.which.co.uk

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>