Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Neurological disease raises risk of complications from flu


Study supports annual flu vaccination for children with neurological conditions

As another flu season approaches, patients with neurological and neuromuscular disease are especially vulnerable to respiratory failure caused by influenza. Researchers from The Children’s Hospital of Philadelphia identified this high-risk group of patients, who have recently been added to the list of groups for whom the federal government recommends receiving annual influenza vaccine.

The research is published in the November 2 issue of the Journal of the American Medical Association. The neurological and neuromuscular diseases studied include cerebral palsy, hydrocephalus, muscular dystrophies, spinal muscular atrophy and seizure disorders.

"Our findings support the recent decision of the Advisory Committee on Immunization Practices [ACIP] to add neurological and neuromuscular disease to the list of chronic conditions that warrant annual influenza vaccination," said study leader Ron Keren, M.D., M.P.H., a pediatrician at The Children’s Hospital of Philadelphia. "We hope this news will reach parents of children with these diseases, as well as health care providers."

The ACIP, an expert panel that advises the CDC on national vaccine practice, had previously designated nine groups of chronic medical conditions for which a flu shot is recommended. Among those conditions are asthma, chronic lung disease, heart disease, disorders of hemoglobin such as sickle cell disease, and chronic kidney disease. The Children’s Hospital study considered all those conditions, in addition to neurological and neuromuscular disease, gastroesophageal reflux disease, and history of prematurity.

The researchers studied the hospital records for 745 children hospitalized at Children’s Hospital for influenza during the 2000 to 2004 flu seasons. Of that total, 32 children (4 percent) developed respiratory failure and needed mechanical ventilation. Of all the chronic conditions studied, children with neurological and neuromuscular disease were at the highest risk of respiratory failure, followed by chronic pulmonary disease other than asthma, and cardiac disease.

The link between neurological disease and respiratory failure among children with flu was a new finding, but not surprising, said Dr. Keren. "Children with neurological and neuromuscular disease often have diminished pulmonary function and ability to handle secretions at baseline, and therefore are more vulnerable to respiratory complications of influenza infection."

Rachel Salis-Silverman | EurekAlert!
Further information:

More articles from Health and Medicine:

nachricht Scientists develop tiny tooth-mounted sensors that can track what you eat
22.03.2018 | Tufts University

nachricht NIH scientists describe potential antibody treatment for multidrug-resistant K. pneumoniae
14.03.2018 | NIH/National Institute of Allergy and Infectious Diseases

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers Discover New Anti-Cancer Protein

An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.

The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...

Im Focus: Researchers at Fraunhofer monitor re-entry of Chinese space station Tiangong-1

In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.

Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...

Im Focus: Alliance „OLED Licht Forum“ – Key partner for OLED lighting solutions

Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.

They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...

Im Focus: Mars' oceans formed early, possibly aided by massive volcanic eruptions

Oceans formed before Tharsis and evolved together, shaping climate history of Mars

A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...

Im Focus: Tiny implants for cells are functional in vivo

For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.

In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

Virtual reality conference comes to Reutlingen

19.03.2018 | Event News

Ultrafast Wireless and Chip Design at the DATE Conference in Dresden

16.03.2018 | Event News

International Tinnitus Conference of the Tinnitus Research Initiative in Regensburg

13.03.2018 | Event News

Latest News

Modular safety concept increases flexibility in plant conversion

22.03.2018 | Trade Fair News

New interactive map shows climate change everywhere in world

22.03.2018 | Earth Sciences

New technologies and computing power to help strengthen population data

22.03.2018 | Earth Sciences

Science & Research
Overview of more VideoLinks >>>