Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Precision radiation therapy yields rare success for liver tumors

19.10.2005


Shaped-beam radiation therapy is a promising treatment for life-threatening metastatic liver tumors, according to researchers at the University of Rochester Medical Center who report an 88 percent success rate for controlling the lesions. This is the first evidence that doctors can treat these tumors with radiation, and the results doubled the average length of survival.



"Radiation therapy has not been a recommended treatment for liver metastases because of the poor results when whole-liver radiation was used," said Alan Katz, M.D., M.P.H., lead researcher and assistant professor of Radiation Oncology. "High-dose, precision radiation therapy is proving to be a promising therapy for metastatic liver disease and provides an effective treatment option for patients who previously didn’t have any."

Radiation oncologists at the University’s James P. Wilmot Cancer Center are leading the effort to expand shaped-beam radiation therapy – originally designed to treat brain tumors – to target metastatic liver tumors with pinpoint accuracy. Initial treatment results were presented this week at the American Society for Therapeutic Radiology and Oncology’s annual meeting in Denver.


Many forms of cancer are treated with radiation therapy, but tumors in the liver are difficult to target using conventional techniques because the organ moves during breathing. Shaped-beam radiation therapy, also known as stereotactic body radiation therapy, has expanded treatment options by delivering a high dose of radiation precisely to the tumor, while limiting the damage to healthy tissue surrounding the tumor.

In Rochester, doctors treated 72 patients with metastatic liver lesions between April 2001 and October 2004. Most of the patients had colorectal, breast, pancreatic, lung, genitourinary, esophageal and ovarian cancers, which had spread to the liver. The patients had a median of two lesions that ranged from 0.5 centimeters to 12.2 centimeters in diameter.

Doctors followed the patients’ progress for an average of a year, though some were followed as long as three years, and the average survival was 13 months.

"This is remarkable. For people who are facing this deadly disease, doubling the length of survival brings hope to our patients and that is so important," Katz said.

Katz led the research, along with Paul Okunieff, M.D., chair of Radiation Oncology, Michael Schell, Ph.D., Christine Huggins, Ph.D., and Madeleine Carey Sampson, M.D.

The Wilmot Cancer Center has been leading the research into expanding the use of stereotactic radiation therapy to treat tumors throughout the body. For the past five years, radiation oncologists have been studying its use in treating a variety of primary and metastatic tumors throughout the body and developing models for delivering radiation to organs that cannot be immobilized, such as the lungs and liver.

Leslie White | EurekAlert!
Further information:
http://www.urmc.rochester.edu

More articles from Health and Medicine:

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

nachricht The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>