Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Precision radiation therapy yields rare success for liver tumors

19.10.2005


Shaped-beam radiation therapy is a promising treatment for life-threatening metastatic liver tumors, according to researchers at the University of Rochester Medical Center who report an 88 percent success rate for controlling the lesions. This is the first evidence that doctors can treat these tumors with radiation, and the results doubled the average length of survival.



"Radiation therapy has not been a recommended treatment for liver metastases because of the poor results when whole-liver radiation was used," said Alan Katz, M.D., M.P.H., lead researcher and assistant professor of Radiation Oncology. "High-dose, precision radiation therapy is proving to be a promising therapy for metastatic liver disease and provides an effective treatment option for patients who previously didn’t have any."

Radiation oncologists at the University’s James P. Wilmot Cancer Center are leading the effort to expand shaped-beam radiation therapy – originally designed to treat brain tumors – to target metastatic liver tumors with pinpoint accuracy. Initial treatment results were presented this week at the American Society for Therapeutic Radiology and Oncology’s annual meeting in Denver.


Many forms of cancer are treated with radiation therapy, but tumors in the liver are difficult to target using conventional techniques because the organ moves during breathing. Shaped-beam radiation therapy, also known as stereotactic body radiation therapy, has expanded treatment options by delivering a high dose of radiation precisely to the tumor, while limiting the damage to healthy tissue surrounding the tumor.

In Rochester, doctors treated 72 patients with metastatic liver lesions between April 2001 and October 2004. Most of the patients had colorectal, breast, pancreatic, lung, genitourinary, esophageal and ovarian cancers, which had spread to the liver. The patients had a median of two lesions that ranged from 0.5 centimeters to 12.2 centimeters in diameter.

Doctors followed the patients’ progress for an average of a year, though some were followed as long as three years, and the average survival was 13 months.

"This is remarkable. For people who are facing this deadly disease, doubling the length of survival brings hope to our patients and that is so important," Katz said.

Katz led the research, along with Paul Okunieff, M.D., chair of Radiation Oncology, Michael Schell, Ph.D., Christine Huggins, Ph.D., and Madeleine Carey Sampson, M.D.

The Wilmot Cancer Center has been leading the research into expanding the use of stereotactic radiation therapy to treat tumors throughout the body. For the past five years, radiation oncologists have been studying its use in treating a variety of primary and metastatic tumors throughout the body and developing models for delivering radiation to organs that cannot be immobilized, such as the lungs and liver.

Leslie White | EurekAlert!
Further information:
http://www.urmc.rochester.edu

More articles from Health and Medicine:

nachricht Cystic fibrosis alters the structure of mucus in airways
29.06.2017 | University of Iowa Health Care

nachricht Mice provide insight into genetics of autism spectrum disorders
28.06.2017 | University of California - Davis

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making Waves

Computer scientists use wave packet theory to develop realistic, detailed water wave simulations in real time. Their results will be presented at this year’s SIGGRAPH conference.

Think about the last time you were at a lake, river, or the ocean. Remember the ripples of the water, the waves crashing against the rocks, the wake following...

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Nanostructures taste the rainbow

29.06.2017 | Physics and Astronomy

New technique unveils 'matrix' inside tissues and tumors

29.06.2017 | Life Sciences

Cystic fibrosis alters the structure of mucus in airways

29.06.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>