Anaesthetic agents are potentially dangerous drugs, and major patient complications can occur. If the patient is overdosed, death or major body organ damage can occur. Conversely, if the patient is under-dosed, patient awareness can occur. There is a narrow drug concentration “window” for both drug safety and anaesthetic efficacy, and the development of ways in which to monitor drug delivery concentration has been a major driver in anaesthetic agent safety research.
The Oxford invention has met this anaesthesia challenge by using modified statistical techniques to classify the physiological state of a human or animal subject. The classification monitors changes in the physiological state that occur over time either spontaneously or from external stimuli. Analysis of data obtained from anaesthetic trials has demonstrated the efficacy of the method for monitoring the depth of anaesthesia.
As well as using encephalograms the invention may be used advantageously with other forms of physiological data: electromyography to indicate muscle activity; analysis of images from magnetic resonance, computed tomography, X-ray and ultrasound; electrocardiography for blood pressure and blood oxygenation. The method also has many other applications including the monitoring of: consciousness, sleep, neuropathology, cerebral intoxication, cognitive state and muscle tremor.
David Eastham | alfa
3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg
Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...
A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.
Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...
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