Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Incremental cost-effectiveness of 2 drug-eluting stents compared to a new generation bare-metal stent in a ‘real-world’ setting

06.09.2005


Repeat interventions to treat restenosis are the Achilles heal of stenting. The new drug-eluting stents (DES) have reduced the need for repeat interventions significantly compared to bare-metal stents (BMS), however, they are so much more expensive, that their use in all patients threatens to ‘kill’ hospital budgets. This has led to difficult discussions among physicians, patients and hospital administrators with regard to who should or could get DES and it was questioned whether withholding DES for cost reasons would not be rationing.



The prospective, randomised, controlled Basel stent cost effectiveness trial (BAsel Stent Kosten Effektivitäts Trial, BASKET) answers these questions for the first time based on 826 consecutive patients treated with PCI and stenting at the University Hospital of Basel, Switzerland. Results presented in Stockholm will show whether DES are worth their price in all patients or whether at least certain patient groups can be identified in which they are cost-effective.

All patients treated with PCI and stenting over a one year period were randomised to receive a DES or a BMS irrespective of indication and risk for restenosis. Three fifths of patients presented with acute infarction or unstable coronary disease and more than two thirds had multivessel disease, not different between the three groups. Patients were treated with nearly two stents each for a total stent length of more than 30 mm per patient.


All patients were followed for 6 months for occurrence of death, non-fatal infarction and target vessel revascularization as well as for cost (baseline, stent and follow-up costs). Results will be presented as difference in costs between DES and BMS in relation to difference in major cardiac events between the two stent types and among the two DES tested. Subgroup analyses will indicate whether this incremental cost-effectiveness ratio is different in certain high risk subgroups such as patients with multivessel disease, small treated vessels, diabetes, long treated segments or those treated in acute coronary syndromes compared with low risk patients.

These findings may have an important impact on the use of DES in daily practice in view of their high cost and also on preferences for one of the two DES. This is particularly true since BASKET was performed entirely independently from the device industry, a reason why the eagerly awaited detailed results can only be revealed in Stockholm.

Gina Dellios | alfa
Further information:
http://www.escardio.org
http://www.escardio.org/vpo/ESC_congress_information/ConferenceReleases/

More articles from Health and Medicine:

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

nachricht The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>