Virtual colonoscopy shows cancer outside the colon
Computed tomographic colonography (CTC) depicts cancers and other clinically important conditions that would be missed with standard colonoscopy and at very little additional cost, according to a study in the August issue of Radiology.
"The chance of finding cancer outside the colon may be as significant as the chance of finding cancer inside the colon," said Judy Yee, M.D., Chief of Radiology at the Veterans Affairs Medical Center and associate professor and Vice Chair of radiology at University of California San Francisco School of Medicine.
CTC, also known as virtual colonoscopy, is a non-invasive screening method for colon cancer. Virtual colonoscopy uses a series of CT images to visually reconstruct the interior of the colon on a computer. Unlike standard colonoscopy--which explores only the interior of the colon, virtual colonoscopy depicts the surrounding areas as well.
"Using the same amount of radiation as a non-contrast CT scan of the abdomen/pelvis, you can do a virtual colonoscopy and screen the surrounding abdominal and pelvic area," Dr. Yee said.
To evaluate the prevalence of extracolonic findings at virtual colonoscopy and to determine the cost of follow-up testing, Dr. Yee and colleagues performed CTC on 500 men, including 194 (39 percent) considered average risk and 306 (61 percent) at high risk for colon cancer. The mean age of the men was 62.5. Of the 500 patients in the study, 315 (63 percent) had extracolonic findings. Forty-five (9 percent) patients had clinically important extracolonic findings.
Findings deemed clinically important included large aneurysms, suspicious lesions and masses in the solid organs of the abdomen, lymphadenopathy, pulmonary nodules and gallbladder wall thickening. The mean additional cost per CTC exam to work up the important findings was $28.12.
"The fact that the additional cost was so low indicates that this procedure is potentially cost effective, not only in regards to the colonoscopy but for other conditions as well," Dr. Yee said.
Dr. Yees research represents the longest follow-up (3.6 years) of patients after CTC and is one of the first to include average-risk patients among the study cohort. There was no significant difference between the numbers of clinically important findings in average- and high-risk patients.
Maureen Morley | EurekAlert!
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Detailed calculations show water cloaks are feasible with today's technology
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...