Virtual colonoscopy shows cancer outside the colon
Computed tomographic colonography (CTC) depicts cancers and other clinically important conditions that would be missed with standard colonoscopy and at very little additional cost, according to a study in the August issue of Radiology.
"The chance of finding cancer outside the colon may be as significant as the chance of finding cancer inside the colon," said Judy Yee, M.D., Chief of Radiology at the Veterans Affairs Medical Center and associate professor and Vice Chair of radiology at University of California San Francisco School of Medicine.
CTC, also known as virtual colonoscopy, is a non-invasive screening method for colon cancer. Virtual colonoscopy uses a series of CT images to visually reconstruct the interior of the colon on a computer. Unlike standard colonoscopy--which explores only the interior of the colon, virtual colonoscopy depicts the surrounding areas as well.
"Using the same amount of radiation as a non-contrast CT scan of the abdomen/pelvis, you can do a virtual colonoscopy and screen the surrounding abdominal and pelvic area," Dr. Yee said.
To evaluate the prevalence of extracolonic findings at virtual colonoscopy and to determine the cost of follow-up testing, Dr. Yee and colleagues performed CTC on 500 men, including 194 (39 percent) considered average risk and 306 (61 percent) at high risk for colon cancer. The mean age of the men was 62.5. Of the 500 patients in the study, 315 (63 percent) had extracolonic findings. Forty-five (9 percent) patients had clinically important extracolonic findings.
Findings deemed clinically important included large aneurysms, suspicious lesions and masses in the solid organs of the abdomen, lymphadenopathy, pulmonary nodules and gallbladder wall thickening. The mean additional cost per CTC exam to work up the important findings was $28.12.
"The fact that the additional cost was so low indicates that this procedure is potentially cost effective, not only in regards to the colonoscopy but for other conditions as well," Dr. Yee said.
Dr. Yees research represents the longest follow-up (3.6 years) of patients after CTC and is one of the first to include average-risk patients among the study cohort. There was no significant difference between the numbers of clinically important findings in average- and high-risk patients.
Maureen Morley | EurekAlert!
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.
Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...
Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.
Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...
Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.
As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...
Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.
With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...
Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine
Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...