New knowledge can improve current therapies and shape new ones Researchers have determined how metabolic pathways differ between healthy and failing hearts. Normally, a heart derives its energy from a balance of fatty acids and carbohydrates, specifically glucose.
But Dr. Gary Lopaschuk, a pharmacologist and professor in the University of Alberta Department of Pediatrics, and his colleagues in the U.S. and Italy have found that during the early stages of heart failure, the heart uses too much fatty acid and not enough carbohydrate; and then, later on, the heart doesnt use enough fat.
Lopaschuk thinks that better treatments for heart failure patients may be available now that they have discovered that the type of "fuel" that the heart uses can contribute to the severity of heart failures. There are existing drugs that can make the heart more productive, but they dont remedy the fact that the heart is still inefficient because a lot of oxygen is necessary for it to drive the same amount of contractile activity.
Ryan Smith | EurekAlert!
Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena
Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
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