Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Mayo Clinic Finds Kidney Disease Associated with "Benign" Prostate Obstruction

30.06.2005


Men who experience signs and symptoms of a prostate obstruction resulting from benign prostatic hyperplasia (BPH) are three times more likely than other men to develop chronic kidney disease, according to findings of a Mayo Clinic study published in this month’s edition of Kidney International.



"This is the first study on the topic to sample the general community," says Andrew Rule, M.D., the Mayo Clinic kidney specialist who conducted the study with epidemiologist Steven Jacobsen, M.D., Ph.D.

"Symptomatic and non-symptomatic men were compared, unlike clinical trials and studies in a urology practice, which tend to represent only symptomatic men."


BPH and chronic kidney disease pose significant health problems in older men. Chronic kidney disease (CKD) occurs when the kidneys cannot rid metabolic wastes from the body or maintain the proper fluid and chemical balances. Eventually, the waste builds up and becomes poisonous to the body. Kidney disease can develop rapidly -- in two to three months -- or gradually over decades.

Many risks coincide with the development of CKD. "Several studies show men with chronic kidney disease have increased chance of death, hospitalization and cardiovascular events," says Dr. Rule.

The prostate gland is located just below a male’s bladder and surrounds the top portion of the urethra, the tube that drains urine from the bladder. "Growth of the prostate gland can lead to a bladder outlet obstruction," says Dr. Rule. "An obstruction of the bladder can cause inability to or discomfort in emptying the bladder, a slowed stream of urine, frequent urges to void during the night or an enlarged, damaged bladder."

"We were surprised at how much kidney disease can be attributed to BPH," says Dr. Jacobsen. "An obstruction on the urethra is like a dam on a river -- men can still void, but the constant buildup and pressure will ultimately cause damage." BPH affects about half of men in their 60s and up to 90 percent of men in their 70s and 80s. It is not related to the development of prostate cancer, although causes of BPH tissue growth inside the prostate later in life is unclear. Researchers believe that with age the prostate becomes more susceptible to the effects of hormones, including testosterone.

The most effective way to treat CKD is to care for and manage the underlying disease. "It has been shown that many patients with kidney disease respond to surgical treatments of BPH," says Dr. Rule. "There are also medications to relieve obstructions, by either shrinking the prostate gland or relaxing muscles that contribute to the obstruction."

The recent study surveyed 476 white men, ages 40-79, randomly selected from Olmsted County, Minn. Eventually, the researchers would like to see if similar findings are reproduced among general populations studied at other research centers. Dr. Jacobsen also suggests further research and testing to determine if treating BPH reverses the progression of kidney disease.

Ultimately, the researchers hope the results of the study will encourage both physicians and patients to consider BPH as a factor in kidney disease. "Men with diagnosed BPH may need to be screened to see if this condition is causing kidney damage," says Dr. Jacobsen.

Lisa Lucier | EurekAlert!
Further information:
http://www.mayo.edu

More articles from Health and Medicine:

nachricht Using fragment-based approaches to discover new antibiotics
21.06.2018 | SLAS (Society for Laboratory Automation and Screening)

nachricht Scientists learn more about how gene linked to autism affects brain
19.06.2018 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Temperature-controlled fiber-optic light source with liquid core

In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.

Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...

Im Focus: Overdosing on Calcium

Nano crystals impact stem cell fate during bone formation

Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

Towards universal influenza vaccines – is Neuraminidase underrated?

22.06.2018 | Life Sciences

Thermal Radiation from Tiny Particles

22.06.2018 | Physics and Astronomy

Polar ice may be softer than we thought

22.06.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>