Patients with rheumatoid arthritis (RA) are at increased risk of coronary artery disease (CAD) compared with individuals who suffer from CAD but not RA. The findings of research published today in Arthritis Research & Therapy show that CAD is accelerated in RA patients, and patients with both RA and CAD are at an increased risk of death from heart disease. The authors of the study suggest that the high numbers of inflammatory T cells found in RA arthritis patients may cause the increased risk of CAD. Importantly, this increased risk results in a trend towards increased risk of death from cardiovascular disease for patients with rheumatoid arthritis.
The risk of cardiovascular diseases is higher in patients with RA. It is known that the processes leading to the chronic inflammation and autoimmune response seen in RA share features with those involved in atherosclerosis. Because of this, RA patients could be predisposed to CAD. Several studies have already shown an increased risk of atherosclerosis and heart attacks in patients with RA. Despite this knowledge, data is lacking on how high that risk is.
Kenneth Warrington and colleagues, from the Mayo Clinic in Minnesota, conducted a study of residents in Olmsted County, Minnesota, USA, with RA and new-onset CAD. These patients were compared to a control group of patients with newly diagnosed CAD. The two groups were then matched for age, sex and cardiovascular risk factors including diabetes, high blood pressure and smoking. For patients in both groups, the results of the first coronary angiogram – an x-ray image of blood vessels used to identify the exact location and severity of CAD – were examined.
Juliette Savin | alfa
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
22.02.2017 | Power and Electrical Engineering
22.02.2017 | Life Sciences
22.02.2017 | Physics and Astronomy