Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

One-A-Day Tablet Treats Common Infection

06.06.2005


A bioadhesive tablet containing the antifungal drug miconazole is an effective and convenient means of treating oropharyngeal candidiasis, which is the most frequently occurring infection in head and neck cancer patients undergoing radiation therapy, scientists report today at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary.



Dr. Rene-Jean Bensadoun from Centre Antoine Lacassagne in Nice, and international colleagues, studied patients in 36 centers who had completed radiotherapy for head and neck cancer and had oropharyngeal candidiasis confirmed by examination or fungal culture.

One group of 141 patients were given daily a bioadhesive tablet containing 50mg of miconazole, developed by BioAlliance Pharma, a French biopharmaceutical company, the other 141 patients received a mouth gel (MBG) containing 125mg of miconazole four times daily for 14 days.


"We found that the daily bioadhesive buccal tablet achieved the same efficacy as the gel, but required one-tenth as much miconazole, and could be given on a much more convenient schedule," Dr. Bensadoun said.

"Patients currently need to apply the gel four times a day, which is disruptive to their day and increases the risk that they will miss treatments and suffer the discomfort of candidiasis for a longer period of time."

"While oropharyngeal candidiasis is perhaps not a dangerous infection, it is unpleasant, and anything we can do as oncologists to improve the quality of life of cancer patients is a positive thing."

"Head and neck cancer patients suffer not only from their disease, but experience many acute and chronic side-effects due to treatment", comments Dr. Dirk Schrijvers from the Department of Medical Oncology of the ZNA Middelheim, Antwerp, Belgium. Everything that can improve the quality of life of these patients during and after treatment will have an impact on treatment compliance and disease outcome. By providing a simpler way of controlling oral candidiasis, patient compliance may increase.

Gracemarie Bricalli | alfa
Further information:
http://www.esmo.org

More articles from Health and Medicine:

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

nachricht High speed video recording precisely measures blood cell velocity
15.11.2017 | ITMO University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

17.11.2017 | Health and Medicine

The importance of biodiversity in forests could increase due to climate change

17.11.2017 | Studies and Analyses

VideoLinks
B2B-VideoLinks
More VideoLinks >>>