A bioadhesive tablet containing the antifungal drug miconazole is an effective and convenient means of treating oropharyngeal candidiasis, which is the most frequently occurring infection in head and neck cancer patients undergoing radiation therapy, scientists report today at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary.
Dr. Rene-Jean Bensadoun from Centre Antoine Lacassagne in Nice, and international colleagues, studied patients in 36 centers who had completed radiotherapy for head and neck cancer and had oropharyngeal candidiasis confirmed by examination or fungal culture.
One group of 141 patients were given daily a bioadhesive tablet containing 50mg of miconazole, developed by BioAlliance Pharma, a French biopharmaceutical company, the other 141 patients received a mouth gel (MBG) containing 125mg of miconazole four times daily for 14 days.
Gracemarie Bricalli | alfa
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