Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Female lung transplant recipients at greater risk of acute lung injury

25.05.2005


Female lung transplant recipients are significantly more likely to suffer from a type of injury to the transplanted lung called primary graft dysfunction than male lung transplant patients, according to a study to be presented at the American Thoracic Society International Conference on May 24.



The study found that female lung transplant recipients who received a lung from either a male or female donor were almost 60% more likely to suffer from primary graft dysfunction, compared with male recipients who received their lung from a male donor.

"There are a number of possible reasons why women are at increased risk," said lead researcher Catherine Kuntz, M.D., Pulmonary Fellow at the Hospital of the University of Pennsylvania. "It may involve women’s hormones or differences in their immune systems."


The study included data on all 7,482 adult lung transplants performed in the United States between 1994 and 2002. The researchers took into account factors such as the donor’s age, race, cause of death, and the recipient’s age, race and reason for lung transplant, as well as the size matching between the donor and recipient.

Overall, approximately 10% of transplant recipients suffered from primary graft dysfunction, which is an acute severe lung injury that occurs within the first 72 hours after the transplant and has a high mortality.

Once the lung is taken out of the donor, it is put on ice, and during this time, no blood flows through the organ. When the lung is transplanted into the recipient and all the blood vessels are reattached, injury to the lung may become apparent. Lung graft dysfunction is associated with a high death rate, prolonged hospital stay and other serious complications.

"We need further investigation into what it is about women that increases the risk," Dr. Kuntz said. "We need to look at factors such as whether the women have gone through menopause, and how many children they’ve had."

According to the United Network for Organ Sharing (UNOS) there are currently 3,688 Americans waiting for a lung transplant for diseases including cystic fibrosis, chronic obstructive pulmonary disease (COPD), primary pulmonary hypertension and pulmonary fibrosis.

Jim Augustine | EurekAlert!
Further information:
http://www.thoracic.org/

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>