Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Guidelines Recommend Screening HIV-Infected Patients for Kidney Disease

28.04.2005


The HIV Medicine Association has released guidelines for managing chronic kidney disease in patients living with HIV infection. They are published in the June 1 issue of Clinical Infectious Diseases, now available online.



The guidelines are the first of their kind. They recommend screening for kidney disease at the time of HIV diagnosis to identify early this serious complication of HIV infection.

Nearly one-third of HIV-infected patients have abnormal amounts of protein in the urine, a warning sign of potential kidney trouble. HIV-related nephropathy (HIVAN) is joining diabetes, hypertension, and hepatitis C infection on the list of common conditions requiring dialysis. Also, kidney disease may be associated with progression to AIDS and death.


The guidelines are targeted toward HIV caregivers, who often manage all aspects of their patients’ care and are therefore in a unique position to identify early those patients at risk for kidney disease. They provide an overview of how to identify patients at risk and evaluate their kidney function, as well as management strategies and other issues.

Samir K. Gupta, MD, MS, lead author of the new guidelines, says, "We’re trying to shift gears from how you treat the HIV-infected patient with severe kidney disease, to how do we look for the ones who are at risk of developing severe kidney disease and taking care of them early so they don’t have to end up going on dialysis."

According to the guidelines, those at high risk of kidney disease include people of African descent, those with low CD4+ cell counts or high viral loads, and people with diabetes, hypertension, or hepatitis C coinfection. All patients diagnosed with HIV should be screened for proteinuria and kidney function.

"One of the major goals of the guidelines is to say we need to be doing screening for patients at higher risk, and if these patients are at higher risk for conditions like HIVAN, then perhaps we should be treating them earlier than we would have otherwise," Dr. Gupta says.

Patients who already have advanced renal disease may still benefit from antiretroviral therapy, Dr. Gupta notes. "A lot of people say, ’Well, I have to tackle somebody’s HIV first and then worry about the kidneys next.’ Fortunately, you may be doing both at the same time." However, some anti-HIV drugs are themselves toxic to the kidneys, so the guidelines also provide calculations to adjust dosages based on the patient’s specific condition.

Dr. Gupta says kidney disease has become more of a concern for people living with HIV/AIDS since the beginning of the era of highly active antiretroviral therapy (HAART).

"Before HAART was available, we needed to help patients survive first. These other conditions, although of concern, took a back seat," Dr. Gupta says. "But now, as patients are living longer and are doing well because of HAART, we’re starting to see these other chronic conditions emerge and become more prevalent."

Research into kidney disease among people living with HIV/AIDS is increasing dramatically, he says. These guidelines are the first to address the issue. He expects they will be updated in a few years as research evolves.

Steve Baragona | EurekAlert!
Further information:
http://www.hivma.org
http://www.idsociety.org

More articles from Health and Medicine:

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

Im Focus: Computer-Designed Customized Regenerative Heart Valves

Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.

Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...

Im Focus: Light-induced superconductivity under high pressure

A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.

Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Supersonic waves may help electronics beat the heat

18.05.2018 | Power and Electrical Engineering

Keeping a Close Eye on Ice Loss

18.05.2018 | Information Technology

CrowdWater: An App for Flood Research

18.05.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>