Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Virtual colonoscopy: Virtually promising

19.04.2005


In an editorial published in the April 19 issue of the Annals of Internal Medicine, Indiana University School of Medicine gastroenterologist Thomas Imperiale, M.D., says virtual colonoscopy may become one of the most valuable assessment tools available for colorectal cancer screening.



"I expect a lot from a screening test — zero risk, high sensitivity, high specificity, reasonable ease and convenience, and cost effectiveness," said Dr. Imperiale, who is professor of medicine and Regenstrief Institute research scientist. "That may be a lot to ask, but I think CT colonography (also known as virtual colonoscopy) has the potential to meet all of these criteria, especially if the need to take a laxative preparation can be eliminated."

"Colonoscopy is currently used as a screening test for colorectal cancer, but it didn’t start out as one," he explained. "The cumulative potential for side effects from the laxative preparation, the need for conscious sedation, lost sleep, time lost from work, the need to arrange for someone to drive the patient home, and risk for perforation exceed my threshold for what a good screening test should be."


Colonoscopy became a common tool for screening primarily by default, he said. "Colonoscopy has evolved into an acceptable screening test in part because many people believe that there are no other good options."

Although it is not yet ready to be used as a screening test, virtual colonoscopy may prove to be highly sensitive, highly specific, reasonably convenient, cost effective, and low risk, according to Dr. Imperiale.

Physicians have come to accept colonoscopy as "the best test" for colorectal cancer because it’s the most accurate test in a single application. Before the popularity of colonoscopy for screening, it was a diagnostic and therapeutic procedure. Unlike colonoscopy, most screening tests only screen for disease. Colonoscopy is a screening test, a diagnostic test and a therapeutic procedure all in one, which may be considered an advantage by some people; however the downsides must be considered.

There are a few examples of truly good screening tests for any cancer, according to Dr. Imperiale, who thinks that PAP smears are probably the best currently available screening tools because they are reasonably sensitive, specific, and inexpensive, and the test itself has no risk.

"To some extent, the absence of a truly good screening test for colorectal cancer has caused us to lower our standards for what a good screening test should be," he said. "If there were a truly good screening test for colorectal cancer, screening rates would be higher than current rates, which are under 50 percent. We need better screening tests, and virtual colonoscopy has the potential to fill that need."

Cindy Fox Aisen | EurekAlert!
Further information:
http://www.iupui.edu

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>