Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Childhood asthma may be linked to grandmother’s smoking

12.04.2005


Dangers of tobacco products transcend generations



A child whose grandmother smoked while pregnant may have double the risk of developing childhood asthma, according to new research. A study published in the April issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians, suggests that the harmful effects of tobacco products can be passed through the generations, even if the damage is not visibly apparent in the second generation.

"This is the first study to show that, if a woman smokes while she is pregnant, both her children and grandchildren may be more likely to have asthma as a result," said the study’s author, Frank D. Gilliland, MD, PhD, Keck School of Medicine of the University of Southern California, Los Angeles, CA. "The findings suggest that smoking could have a long-term impact on a family’s health that has never before been realized."


Researchers from the Keck School of Medicine analyzed data from telephone interviews with parents or guardians of 908 children. A total of 338 of the children had asthma within their first five years of life, and 570 served as a control group. The study showed that children with mothers who smoked while pregnant were 1.5 times more likely to develop asthma early in life, and those children with grandmothers who smoked, while pregnant, were 2.1 times more likely to develop asthma. Further analysis revealed that even if a child’s mother did not smoke while she was pregnant, but the child’s grandmother did, the child was 1.8 times more likely to develop asthma. If both the mother and grandmother smoked while pregnant, a child was 2.6 times more likely to develop asthma.

"A potential explanation for our unexpected results is that when a pregnant woman smokes, the tobacco affects her fetus’s DNA," said Dr. Gilliland. "We speculate that the damage that occurs affects the child’s immune system and increases her susceptibility to asthma, which is then passed down to her children."

Researchers conjecture that when a pregnant woman smokes, biological damage is done to her fetus, and the chemicals from the tobacco can affect the child in two ways. First, if the child is female, her eggs can be affected, which puts her future children at risk. Second, damage may be done to the fetus’s mitochondria, which is then transmitted through the maternal line, as well. Either effect can put a woman’s children and grandchildren at an increased risk of asthma, by decreasing their immune function.

"These findings indicate that there is much more we need to know about the harmful effects of in utero exposure to tobacco products," said Paul A. Kvale, MD, FCCP, President of the American College of Chest Physicians. "They also demonstrate how important smoking cessation is for both the person smoking and their family members."

Arielle Green | EurekAlert!
Further information:
http://www.chestnet.org

More articles from Health and Medicine:

nachricht Speed data for the brain’s navigation system
06.12.2016 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Robot on demand: Mobile machining of aircraft components with high precision

06.12.2016 | Power and Electrical Engineering

A new dead zone in the Indian Ocean could impact future marine nutrient balance

06.12.2016 | Earth Sciences

Significantly more productivity in USP lasers

06.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>