The pathology of rheumatoid arthritis within the first few months after symptom onset is distinct from that of the early phases of other inflammatory joint diseases and also of established rheumatoid arthritis. New research published today in Arthritis Research & Therapy found that very early rheumatoid arthritis is characterised by a distinct profile of T cell, macrophage and stromal cell related cytokines in synovial fluid.
This finding of a distinct phase of rheumatoid arthritis, immediately after the onset of clinical symptoms, provides a new rationale for the very early treatment of rheumatoid arthritis - before the disease develops into a long-term condition.
The synovium, the connective tissue membrane that lines the joints, is the primary site of pathology in rheumatoid arthritis. Although the processes that maintain long-term inflammation of the synovium in rheumatoid arthritis have been well studied, those initiating the inflammation have not, and very few groups have studied the pathology of rheumatoid arthritis within the first few weeks after the onset of symptoms.
Juliette Savin | EurekAlert!
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
22.02.2017 | Power and Electrical Engineering
22.02.2017 | Life Sciences
22.02.2017 | Physics and Astronomy