Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Mountaineering doctors hike medicine to new heights with Xtreme Everest

17.03.2005


Doctors working at the edge of extreme are set to climb the world’s tallest mountain to look death in the face – and take its pulse. The medical research team will make the first ever measurements of blood oxygen in the ‘death zone’, at altitudes above 8,000 metres where the human body has struggled - and frequently failed - to survive.



The Centre for Aviation, Space and Extreme Environment Medicine (CASE) team, based at University College London (UCL), will lead the expedition to Mount Everest’s 8,850m peak in 2007. At the summit, clinicians will measure the amount of oxygen in their own blood along with running tests to see how well their brains, lungs and metabolisms are working at extreme altitude. The experiments alone entail a risk of thrombosis and other complications; combined with the harsh mountain conditions, only the toughest are likely to finish the job.

The summiting team, all of whom work with anaesthesia, intensive care or remote medicine, hope to draw parallels between the human body pushed to its limits during critical illness and changes that occur in extreme environments. Low levels of oxygen in the blood of high altitude climbers is similar to levels in critically ill patients on breathing machines with severe heart and lung conditions, “blue babies” and cystic fibrosis sufferers.


The summiteers will also test a prototype closed-circuit breathing system. This type of circuit has only once previously - and unsuccessfully - been used by climbers attempting the summit. The equipment, adapted from firefighters’ apparatus, will be redesigned to cope with icy conditions.

Overall, the Xtreme Everest expedition will consist of research teams exploring the following science themes: Hypoxia (oxygen deficiency); Brain; Breathing Systems and Genetics. High altitude laboratories set up en route, including one on Everest’s South Col (8,000m), will enable collaborating scientists to investigate many aspects of extreme altitude physiology including illnesses such as fluid on the brain and lungs and acute mountain sickness. The genetics project will track and compare the genetic profile of high altitude natives, lowlanders and summiteers to identify genes that aid survival in extreme altitudes.

A separate initiative called Project Everest will recruit over 1000 volunteers to take part in cardiovascular fitness research at UCL in the run up to the expedition. Participants will undergo Cardiopulmonary Exercise Testing (CPEX) which will measure their heart rate and breathing to determine their maximum exercise potential and endurance, which can then be used to tailor fitness training programmes.

CASE director and expedition leader Dr Mike Grocott says: “If you reached the top of Everest without acclimatizing you would be unconscious within two minutes, and death would follow rapidly. Acclimatization has allowed human beings to survive and thrive in the most extreme conditions, but it remains a poorly understood process. Our goal is to study life at the very limit.”

The core climbing group of seven, two of whom have yet to be recruited, include cardiovascular geneticist Dr Hugh Montgomery, GP Dr Sundeep Dhillon, high altitude clinician Dr Mike Grocott, clinician Dr Roger McMorrow and diving expert Dr Denny Levett. Space expert Dr Kevin Fong along with Dr Levett will act as medics for the expedition teams.

Dr Dhillon is the only participant who has experience of climbing above 8,000m. The others will test their aptitude along with the equipment in two dry runs to Cho Oyu (8,201m) scheduled for the autumns of 2005 and 2006.

For the big push, the expedition plans to set off in the spring of 2007 before the monsoon season, with a ‘window in the weather’ of only a few days when conditions are good enough to attempt the summit. Along with the usual climbing dangers of rockfalls and avalanches, the group will be risking medical complications such as high altitude illness, frostbite, hypothermia and brain damage.

Details of the expedition will be discussed at a conference to be held in London on 27th April 2005. The conference, Lessons Learnt from Life at the Limits, will discuss the parallels between extreme environment physiology and critical care along with the history and future of extreme high altitude research.

Jenny Gimpel | alfa
Further information:
http://www.xtreme-everest.co.uk/Events/main.html
http://www.ucl.ac.uk/media/archive/archive-release/?xteverest

More articles from Health and Medicine:

nachricht Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State

nachricht NTU scientists build new ultrasound device using 3-D printing technology
07.12.2016 | Nanyang Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Closing the carbon loop

08.12.2016 | Life Sciences

Applicability of dynamic facilitation theory to binary hard disk systems

08.12.2016 | Physics and Astronomy

Scientists track chemical and structural evolution of catalytic nanoparticles in 3-D

08.12.2016 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>