A new study by Tulane University researchers, published in the March edition of Molecular Endocrinology, provides insight into one of the ways diethylstilbesterol (DES) may alter the development of the uterus.
DES, a synthetic estrogen, was prescribed to prevent miscarriage in many women who were pregnant between 1941 until 1971. In 1971, DES was banned in the United States due to concerns about the occurrence of cancer and infertility in the daughters of women who took it.
“Several millions of pregnant women were treated with DES and we have continued to study and model the disease since it provides unique insights into what estrogenic chemicals may do to the developing fetus,” says study co-author John McLachlan, director of the Center for Bioenvironmental Research at Tulane and Xavier Universities. “There are other chemicals in our environment -- the results of industrial, agriculture and chemical processing -- that, while their estrogenic affect is weaker, may affect developing embryos in the same way. We need models to understand the cellular and genetic mechanisms by which environmental chemicals work. This study is a step in that direction.”
Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News