Researchers find drugs boost survival in those with congestive heart failure and mitral regurgitation with normal ejection fraction
Beta-blockers, medications that block the action of certain hormones on the heart, can benefit patients with certain serious heart problems such as diastolic heart failure, according to cardiologists at the Keck School of Medicine of the University of Southern California and Loma Linda University Medical Center.
Researchers presented two reports on the use of beta-blockers in patients with chronic severe mitral regurgitation, or MR, and congestive heart failure, CHF, at the American College of Cardiologys 54th Annual Scientific Session on March 7. These patients had a normal ejection fraction, a measure of how well the heart pumps out blood. "Our findings are encouraging because there are no data on the survival benefit of medical therapy in CHF or severe MR patients with normal ejection fraction. CHF with normal ejection fraction, popularly referred to as diastolic heart failure, makes up nearly 50 percent of all CHF patients-and these patients have very similar mortality and morbidity as those with reduced ejection fraction," says Padmini Varadarajan, M.D., advanced cardiac imaging fellow in the Department of Cardiovascular Medicine at the Keck School of Medicine and the studys lead author.
Sarah Huoh | EurekAlert!
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