Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Heart Center cardiologist performs rare liver catheter intervention on teen

08.03.2005


Through an innovative catheterization procedure, a pediatric cardiologist at Texas Children’s Heart Center in Houston repaired a severe liver condition in a 14-year-old male. The doctor used a catheter and septal occluder device that is generally used to close holes in children’s hearts. Similar procedures have been reported only six times in medical literature. But this is the first time the procedure has been performed with this particular device.



"Sammy was born with a hole in his liver about the size of a garden hose that has caused him complicated health problems," said Dr. Henri Justino, an interventional cardiologist at Texas Children’s Heart Center and an assistant professor of pediatrics at Baylor College of Medicine. "Since we successfully perform a wide variety of interventional cardiac procedures in the catheterization lab every day, we consulted with colleagues in the Liver Center, and decided to apply the same procedure in Sammy’s case," said Justino.

Sammy Drake, a resident of West Texas, was born with a rare liver problem known as patent ductus venosus (PDV). The ductus venosus, a large vein that crosses through the liver and empties near the heart, is normally present before birth and plays an important role in the development of the fetus. After birth, however, the PDV is no longer needed and usually closes on its own. Closure of this vein allows blood returning from the intestines to go to the liver, an essential step needed to filter certain nutrients and toxins in foods.


In Drake’s case, the PDV did not close. Instead, it allowed blood returning from the intestines carrying toxic ammonia, to take a shortcut through the PDV directly into the heart and lungs. The high concentration of ammonia in Sammy’s bloodstream was toxic to many organs, including his brain. Ammonia likely contributed to his chronic lung problems, making him so short of breath that it is difficult for him to speak.

Justino performed the unusual catheterization procedure by inserting two long straw-like catheters into the liver through veins in Sammy leg and neck. Once the catheters reached the liver, the doctor was able to locate and measure the size of the PDV by injecting a dye while viewing through an x-ray camera. Justino then deployed a mesh-like occluder device through one of the catheters, thus filling the liver’s large abnormal vein. The new device now blocks the shortcut channel through the liver. Soon, tissue will grow around the mesh and make a complete closure.

"This is an excellent example of cooperation across medical services," says Dr. Saul Karpen, director, Texas Children’s Liver Center and associate professor of pediatrics at Baylor College of Medicine. "Sammy’s ultrasound of the liver looks spectacular, and his now-normal ammonia levels are the lowest they have ever been in his life. Without the procedure to close the PDV, Sammy would possibly require a liver transplant or risk progressive brain damage from the toxic ammonia," Karpen said.

Carol Wittman | EurekAlert!
Further information:
http://www.texaschildrenshospital.org

More articles from Health and Medicine:

nachricht Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Study shines light on brain cells that coordinate movement

26.06.2017 | Life Sciences

Smooth propagation of spin waves using gold

26.06.2017 | Physics and Astronomy

Switchable DNA mini-machines store information

26.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>